The NLRP3 inflammasome in non-alcoholic fatty liver disease and steatohepatitis: Therapeutic targets and treatment

L Yu, W Hong, S Lu, Y Li, Y Guan, X Weng… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is among the most prevalent primary liver
diseases worldwide and can develop into various conditions, ranging from simple steatosis …

[HTML][HTML] Echinacoside: a promising active natural products and pharmacological agents

W Wang, S Jiang, Y Zhao, G Zhu - Pharmacological Research, 2023 - Elsevier
Echinacoside, a natural phenylethanoid glycoside, was discovered and isolated from the
garden plant Echinacea angustifolia DC., belonging to the Compositae family …

Cistanches Herba, from an endangered species to a big brand of Chinese medicine

Y Song, K Zeng, Y Jiang, P Tu - Medicinal Research Reviews, 2021 - Wiley Online Library
Abstract Cistanches Herba (CH, Chinese name: Roucongrong), is a very precious, tonic
Chinese medicine. Cistanche deserticola and Cistanche tubulosa are the two commonly …

Exploration of Osmanthus fragrans Lour.'s composition, nutraceutical functions and applications

L Wu, J Liu, W Huang, Y Wang, Q Chen, B Lu - Food Chemistry, 2022 - Elsevier
Abstract Osmanthus fragrans (Thunb.) Lour. has been cultivated in China for over 2500
years. Due to the unique and strong fragrance, O. fragrans flowers have long been added …

Complete biosynthesis of the phenylethanoid glycoside verbascoside

Y Yang, D **, Y Wu, T Liu - Plant Communications, 2023 - cell.com
Verbascoside, which was first discovered in 1963, is a well-known phenylethanoid glycoside
(PhG) that exhibits antioxidant, anti-inflammatory, antimicrobial, and neuroprotective …

TRPV3 Ion Channel: from gene to Pharmacology

AP Kalinovskii, LL Utkina, YV Korolkova… - International Journal of …, 2023 - mdpi.com
Transient receptor potential vanilloid subtype 3 (TRPV3) is an ion channel with a sensory
function that is most abundantly expressed in keratinocytes and peripheral neurons. TRPV3 …

Echinacoside upregulates Sirt1 to suppress endoplasmic reticulum stress and inhibit extracellular matrix degradation in vitro and ameliorates osteoarthritis in vivo

Z Lin, C Teng, L Ni, Z Zhang, X Lu, J Lou… - Oxidative medicine …, 2021 - Wiley Online Library
Background. Osteoarthritis (OA) is a progressive illness that destroys cartilage. Oxidative
stress is a major contributor of OA, while endoplasmic reticulum (ER) stress is the key …

Acteoside, the Main Bioactive Compound in Osmanthus fragrans Flowers, Palliates Experimental Colitis in Mice by Regulating the Gut Microbiota

Y Liu, W Huang, Y Zhu, T Zhao, F **ao… - Journal of Agricultural …, 2022 - ACS Publications
The present study investigated the effects of Osmanthus fragrans flowers and acteoside on
murine colitis and the underlying mechanisms. The O. fragrans flower extract (OFE) and …

Echinacoside induces mitochondria‐mediated pyroptosis through Raf/MEK/ERK signaling in non‐small cell lung cancer cells

Y Shi, H Cao, Z Liu, L **, C Dong - Journal of Immunology …, 2022 - Wiley Online Library
Background. Various natural compounds are effective in cancer prevention and treatment
with fewer side effects than conventional radiotherapy and chemotherapy. Considering the …

Verbascoside: comprehensive review of a phenylethanoid macromolecule and its journey from nature to bench

R Saha, A Majie, R Baidya, B Sarkar - Inflammopharmacology, 2024 - Springer
Polyphenolic compounds are among the most widely researched compounds for various
therapeutic applications. However, naturally occurring phenylethanoid glycosides are least …