Evolution in coeliac disease diagnosis and management

JA Tye‐Din - JGH Open, 2024 - Wiley Online Library
The traditional gut‐centric view of coeliac disease is evolving as immune and genetic
insights underscore the central importance of a systemic, T cell immune response to gluten …

Role of endoscopy in the diagnosis of coeliac disease: a narrative review

MG Shiha, A Yusuf, DS Sanders - Translational …, 2024 - pmc.ncbi.nlm.nih.gov
Background and Objective Coeliac disease (CD) is a common autoimmune disorder
triggered by gluten consumption in genetically predisposed individuals. CD is characterised …

Patient preferences for the diagnosis of coeliac disease: A discrete choice experiment

MG Shiha, N Wickramasekera, SA Raju… - United European …, 2024 - Wiley Online Library
Background There is potential for a paradigm shift from a biopsy‐to a serology‐based
diagnosis of coeliac disease in selected adult patients. However, it remains unknown if this …

Clinical outcomes of potential coeliac disease: a systematic review and meta-analysis

MG Shiha, A Schiepatti, S Maimaris, NI Nandi… - Gut, 2024 - gut.bmj.com
Objective Potential coeliac disease (PCD) is characterised by positive serological and
genetic markers of coeliac disease with architecturally preserved duodenal mucosa. The …

Patient perceptions of the Finnish guidelines enabling coeliac disease diagnosis without biopsies in adults

H Sareila, K Kurppa, H Huhtala, P Laurikka… - Scandinavian Journal …, 2025 - Taylor & Francis
Objectives Diagnosis of coeliac disease based on serology only has been allowed since
2018 in Finland for adults meeting specific criteria. We studied the patient experiences and …

Preparation and Immunochemical Characterization of a Water-Soluble Gluten Peptide Fraction for Improving the Diagnosis of Celiac Disease

N Meyer, B Illarionov, M Fischer, H Wieser - Nutrients, 2024 - mdpi.com
The diagnosis of celiac disease (CD) is complex and requires a multi-step procedure
(symptoms, serology, duodenal biopsy, effect of a gluten-free diet, and optional genetic). The …

Controversies and Opportunities of a Nonbiopsy Diagnosis for Celiac Disease

CL Jansson-Knodell, A Rubio-Tapia… - Gastrointestinal …, 2025 - giendo.theclinics.com
Gastrointest Endoscopy Clin N Am-(2025)-–-https://doi. org/10.1016/j. giec. 2024.12. 010
giendo. theclinics. com 1052-5157/25/© 2025 Elsevier Inc. All rights are reserved, including …

Celiac disease and nonceliac enteropathies

JB Doyle, B Lebwohl - Current Opinion in Gastroenterology, 2024 - journals.lww.com
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What is new in the management of coeliac disease?

MG Shiha, DS Sanders - European Journal of Internal Medicine, 2025 - Elsevier
Coeliac disease is the most common immune-mediated enteropathy, affecting
approximately 1% of the population worldwide. Currently, the vast majority of individuals …

Coeliac disease: the paradox of diagnosing a food hypersensitivity disorder with autoantibodies

MF du Pre, R Iversen, LM Sollid - Gut, 2024 - gut.bmj.com
Serum antibodies to the autoantigen transglutaminase 2 (TG2) are increasingly harnessed
to diagnose coeliac disease. Diagnostic guidelines for children give recommendation for a …