Parkinson disease (PD) is the second most common neurodegenerative disorder, affecting>
1% of the population≥ 65 years of age and with a prevalence set to double by 2030. In …

Mild cognitive impairment associated with Parkinson's disease (PD) is a risk factor for the
development of dementia. Despite the importance of early identification of mild cognitive …

Cerebrospinal fluid analyses and neuroimaging can identify the underlying pathophysiology
at the earliest stage of some neurodegenerative disorders, but do not have the scalability …

Autophagy is the process by which cells can selectively or non-selectively remove damaged
proteins and organelles. As the cell's main means of sequestering damaged mitochondria …

Dementia is one of the greatest global challenges for public health; however, the
relationship between anticholinergic drugs and dementia remains unclear. The aim of the …

Mild cognitive changes, including executive dysfunction, are seen in Parkinson's Disease
(PD). Approximately 30% of individuals with PD develop Parkinson's disease dementia …

Cognitive impairment is one of the most salient non-motor symptoms of Parkinson disease
(PD) that poses a significant burden on the patients and carers as well as being a risk factor …

Objective Despite recent attention to cognitive impairment in essential tremor, few studies
examine rates of conversion to diagnoses of mild cognitive impairment and dementia …

Cognitive impairment (CI) is a characteristic non-motor feature of Parkinson disease (PD)
that poses a severe burden on the patients and caregivers, yet relatively little is known about …

Background Early detection of mild cognitive impairment (MCI), a transitional stage between
normal aging and Alzheimer disease, is crucial for preventing the progression of dementia …