There has been recent renewed interest in studying human early embryonic development.
The advent of improved culture conditions to maintain blastocysts in vitro for an extended …

The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …

Gastruloids are a powerful in vitro model of early human development. However, although
elongated and composed of all three germ layers, human gastruloids do not morphologically …

Abstract Development requires coordinated interactions between the epiblast, which
generates the embryo proper; the trophectoderm, which generates the placenta; and the …

Recent advances in methods to culture pluripotent stem cells to model human development
have resulted in entities that increasingly have recapitulated advanced stages of early …

Synthetic embryology aims to develop embryo-like structures from stem cells to provide new
insight into early stages of mammalian development. Recent advances in synthetic …

Cilia are hair‐like structures that project from the surface of cells. In vertebrates, most cells
have an immotile primary cilium that mediates cell signaling, and some specialized cells …

Implantation of the human embryo commences a critical developmental stage that
comprises profound morphogenetic alteration of embryonic and extra-embryonic tissues …

Acute myeloid leukaemia (AML), typically a disease of elderly adults, affects 8 children per
million each year, with the highest paediatric incidence in infants aged 0–2 of 18 per million …

As human life expectancy continues to increase and the birth rate continues to decline, the
phenomenon of aging is becoming more prominent worldwide. Therefore, addressing the …