Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

One of the objectives of the Adolescent Brain Cognitive Development (ABCD) Study
(https://abcdstudy. org/) is to establish a national longitudinal cohort of 9 and 10 year olds …

Prior research has shown that acute subjective psychedelic effects are associated with both
spontaneous and intended changes in depression and anxiety. Psychedelics are also …

Gut microbiota in interaction with intestinal host tissues influences many brain functions and
microbial dysbiosis has been linked with brain disorders, such as neuropsychiatric …

The present study investigated interactions between the novel psychoactive tryptamines
DiPT, 4-OH-DiPT, 4-OH-MET, 5-MeO-AMT, and 5-MeO-MiPT at monoamine receptors and …

Rationale Major depressive disorder is one of the leading global causes of disability, for
which the classic serotonergic psychedelics have recently reemerged as a potential …

Background: Ayahuasca, a traditional Amazonian decoction with psychoactive properties, is
made from bark of the Banisteriopsis caapi vine (containing beta-carboline alkaloids) and …

This report provides a historical overview of research concerning the endogenous
hallucinogen N, N-dimethyltryptamine (DMT), focusing on data regarding its biosynthesis …

Abstract Background and Aims Hallucinogen use is potentially harmful. Information on
whether such use has increased in recent decades is lacking. This study assessed overall …

Ayahuasca is a hallucinogen brew traditionally used for ritual and therapeutic purposes in
Northwestern Amazon. It is rich in the tryptamine hallucinogens dimethyltryptamine (DMT) …