Repurposing simvastatin in cancer treatment: an updated review on pharmacological and nanotechnological aspects

N Ara, A Hafeez, SP Kushwaha - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
Management of cancer is challenging due to non-targeting and high side effect issues. Drug
repurposing is an innovative method for employing medications for other disease therapy in …

Preparation and characterization of Sorafenib nano-emulsion: impact on pharmacokinetics and toxicity; an in vitro and in vivo study

D Zaafar, HMA Khalil, GE Elkhouly, AS Sedeky… - Drug Delivery and …, 2024 - Springer
Hepatocellular carcinoma (HCC) ranks as the third leading cause of cancer-related deaths
worldwide. Current treatment strategies include surgical resection, liver transplantation, liver …

Preparation and characterization of nano-emulsion formulations of Asparagus densiflorus root and aerial parts extracts: evaluation of in-vitro antibacterial and …

MS Mady, Y Sobhy, A Orabi, M Sharaky… - Drug Development …, 2024 - Taylor & Francis
Objective Preparation and characterization of nano-emulsion formulations for Asparagus
densiflorus aerial and root parts extracts. Significance Genus Asparagus is known for its …

Hispolon-loaded lipid nanocapsules for the management of hepatocellular carcinoma: comparative study with solid lipid nanoparticles and suspension

NK Alruwaili, WH Almalki, SS Almujri, A Alhamyani… - …, 2024 - Taylor & Francis
Aim: The present study aims to develop, optimize and assess hispolon (HPN) lipid
nanocapsules (LNCs), solid lipid nanoparticles (SLNs) and suspension for treating …