Parkinson disease (PD) is a progressive disorder characterized by dopaminergic
neurodegeneration in the brain. The development of parkinsonism is preceded by a long …

Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …

Abstract Background Patients with Parkinson's disease experience visual symptoms,
partially originating from retinal changes. Since 2011, multiple case-control studies using …

Alzheimer disease (AD) is a chronic neurodegenerative disease that accounts for 60–70%
of dementia and is the sixth leading cause of death in the United States. The pathogenesis …

Optical coherence tomography (OCT) is a widely used biomedical imaging tool, primarily in
ophthalmology to diagnose and stage retinal diseases. In order to increase access for a …

Objective To analyze the relationship between retinal thinning and nigral dopaminergic loss
in de novo Parkinson disease (PD). Methods Forty-nine patients with PD and 54 age …

Increasing evidence suggests that the conditions of retinal microvessels are indicators to a
variety of cerebrovascular, neurodegenerative, psychiatric, and developmental diseases …

Background and purpose Central retina imaging is important for early Parkinson's disease
(PD) recognition. We aimed to investigate central retina changes using spectral domain …

Parkinson's Disease (PD) is the second most common neurodegenerative disease
worldwide, affecting 1% of the population over 65 years of age. Dopaminergic cell death in …

Abstract DARC (Detection of Apoptosing Retinal Cells) is a retinal imaging technology that
has been developed within the last 2 decades from basic laboratory science to Phase 2 …