Oral modified release multiple-unit particulate systems: compressed pellets, microparticles and nanoparticles

N Al-Hashimi, N Begg, RG Alany, H Hassanin… - Pharmaceutics, 2018 - mdpi.com
Oral modified-release multiparticulate dosage forms, which are also referred to as oral
multiple-unit particulate systems, are becoming increasingly popular for oral drug delivery …

Quality by design (QbD) approaches for the compression step of tableting

I Tho, A Bauer-Brandl - Expert opinion on drug delivery, 2011 - Taylor & Francis
Introduction: Although tableting is one of the most commonly used processes in drug
manufacturing, the tablet formation process is still not fully understood, nor can it be fully …

Quality by Design (QbD) approach to optimize the formulation of a bilayer combination tablet (Telmiduo®) manufactured via high shear wet granulation

AR Lee, SY Kwon, DH Choi, ES Park - International journal of …, 2017 - Elsevier
A bilayer tablet, which consisted of telmisartan and amlodipine besylate, was formulated
based on a Quality by Design (QbD) approach. The control and response factors were …

CFD-DEM numerical study on air impacted packing densification of equiaxed cylindrical particles

D Gou, W Fan, B Zhou, X An, R Yang, K Dong… - Advanced Powder …, 2022 - Elsevier
Abstract A CFD-DEM model was developed to reproduce the packing densification process
of mono-sized equiaxed cylindrical particles under air impact. The effects of operating …

A PDE patch-based spectral method for progressive mesh compression and mesh denoising

Q Shen, Y Sheng, C Chen, G Zhang, H Ugail - The Visual Computer, 2018 - Springer
The development of the patchwise partial differential equation (PDE) framework a few years
ago has paved the way for the PDE method to be used in mesh signal processing. In this …

Application of a piston equation to describe die compaction of powders

G Aryanpour, M Farzaneh - Powder Technology, 2015 - Elsevier
Compaction of metal powders in a rigid die is an important step in the fabrication of parts by
the conventional powder metallurgy (P/M) route. It is thus important to find out the …

Automatic shape optimisation of pharmaceutical tablets using Partial Differential Equations

N Ahmat, GG Castro, H Ugail - Computers & Structures, 2014 - Elsevier
Pharmaceutical tablets have been the most dominant form for drug delivery and most of
them are used in the oral administration of drugs. These tablets need to be strong enough so …

ME_expert 2.0: a heuristic decision support system for microemulsions formulation development

A Mendyk, J Szlȩk, R Jachowicz - Formulation tools for pharmaceutical …, 2013 - Elsevier
Artificial neural networks (ANN) and random forest (RF) classifier were employed to model
microemulsions (ME) formation. The ME quantitative and qualitative composition was the …

Measuring the distance of moving objects from big trajectory data

KP Wai, N Nwe - International Journal of Networked and Distributed …, 2017 - Springer
Location-based services have become important in social networking, mobile applications,
advertising, traffic monitoring, and many other domains. The growth of location sensing …