Biological, biochemical and physical stimuli activate inflammatory leukocytes, such as
macrophages, resulting in induction and synthesis of proinflammatory proteins and …

Type 2 diabetes mellitus (T2DM) is a multifaceted metabolic syndrome defined through the
dysfunction of pancreatic β-cells driven by a confluence of genetic and environmental …

Although spices have been used for thousands of years and are known for their flavor, taste
and color in the food, they are not usually recognized for their medicinal value. Extensive …

Cancer is a hyperproliferative disorder that involves transformation, dysregulation of
apoptosis, proliferation, invasion, angiogenesis and metastasis. Extensive research during …

Zerumbone (ZER), a sesquiterpene from the edible plant Zingiber zerumbet Smith, has
recently been found to suppress tumor promoter 12-O-tetradecanoylphorbol-13-acetate …

Abstract Luteolin, 3', 4', 5, 7-tetrahydroxyflavone, belongs to a group of naturally occurring
compounds called flavonoids that are found widely in the plant kingdom. It possesses many …

Zerumbone found in subtropical ginger Zingiber zerumbet Smith exhibits antiproliferative
and antiinflammatory activities but underlying molecular mechanisms are poorly understood …

Phytochemicals and their synthetic derivatives are making a significant contribution in
modern drug discovery programs by targeting several human diseases, including cancer …

We recently showed that zerumbone, a sesquiterpene found in subtropical ginger,
suppresses colonic tumor marker formation in rats and induces apoptosis in colon cancer …

Zerumbone (ZER), a sesquiterpene compound occurring in tropical ginger Zingiber
zerumbet Smith, has been implicated as one of the promising chemopreventive agents …