Therapeutically harnessing extracellular vesicles
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …
from the study of fundamental biology to a subject of significant clinical relevance. The …
Immune cells-derived exosomes function as a double-edged sword: role in disease progression and their therapeutic applications
Exosomes, ranging in size from 30 to 150 nm as identified initially via electron microscopy in
1946, are one of the extracellular vesicles (EVs) produced by many cells and have been the …
1946, are one of the extracellular vesicles (EVs) produced by many cells and have been the …
Emerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applications
J De Toro, L Herschlik, C Waldner… - Frontiers in …, 2015 - frontiersin.org
From the time when they were first described in the 1970s by the group of Johnstone and
Stahl, exosomes are a target of constant research. Exosomes belong to the family of …
Stahl, exosomes are a target of constant research. Exosomes belong to the family of …
Extracellular vesicles exploit viral entry routes for cargo delivery
HM Van Dongen, N Masoumi, KW Witwer… - Microbiology and …, 2016 - Am Soc Microbiol
Extracellular vesicles (EVs) have emerged as crucial mediators of intercellular
communication, being involved in a wide array of key biological processes. Eukaryotic cells …
communication, being involved in a wide array of key biological processes. Eukaryotic cells …
Exosomes and their role in the life cycle and pathogenesis of RNA viruses
Exosomes are membrane-enclosed vesicles actively released into the extracellular space,
whose content reflect the physiological/pathological state of the cells they originate from …
whose content reflect the physiological/pathological state of the cells they originate from …
Exosomes in pathogen infections: a bridge to deliver molecules and link functions
W Zhang, X Jiang, J Bao, Y Wang, H Liu… - Frontiers in …, 2018 - frontiersin.org
Exosomes are extracellular vesicles derived from cell endocytosis which act as transmitters
between cells. They are composed of proteins, lipids, and RNAs through which they …
between cells. They are composed of proteins, lipids, and RNAs through which they …
The versatile role of exosomes in human retroviral infections: from immunopathogenesis to clinical application
Eukaryotic cells produce extracellular vesicles (EVs) mediating intercellular communication.
These vesicles encompass many bio-molecules such as proteins, nucleic acids, and lipids …
These vesicles encompass many bio-molecules such as proteins, nucleic acids, and lipids …
Presence of Tat and transactivation response element in spinal fluid despite antiretroviral therapy
Objective: The aim of this study was to measure the protein concentration and biological
activity of HIV-1 Tat in cerebrospinal fluid (CSF) of individuals on suppressive antiretroviral …
activity of HIV-1 Tat in cerebrospinal fluid (CSF) of individuals on suppressive antiretroviral …
A comprehensive insight into the role of exosomes in viral infection: dual faces bearing different functions
Extracellular vesicles (EVs) subtype, exosome is an extracellular nano-vesicle that sheds
from cells' surface and originates as intraluminal vesicles during endocytosis. Firstly, it was …
from cells' surface and originates as intraluminal vesicles during endocytosis. Firstly, it was …
Extracellular vesicles and viruses: two intertwined entities
Viruses share many attributes in common with extracellular vesicles (EVs). The cellular
machinery that is used for EV production, packaging of substrates and secretion is also …
machinery that is used for EV production, packaging of substrates and secretion is also …