Background Pharmacotherapy in the elderly population is complicated by several factors
that increase the risk of drug‐related harms and less favourable effectiveness. The concept …

Aims Medicine‐related problems (MRP s) represent a major issue leading to hospitalization,
especially in adult and elderly patients. The aims of this review are to investigate the …

Background Numerous observational studies suggest that preventable adverse drug
reactions are a significant burden in healthcare, but no meta-analysis using a standardised …

Objective: Most medications are prescribed, dispensed, and administered in ambulatory
care settings, yet little information exists on the adverse effects of drugs in this setting. This …

Background The significant impact of medication administration errors affect patients in
terms of morbidity, mortality, adverse drug events, and increased length of hospital stay. It …

Background: Little information is available on the potential association between
polypharmacy and risk of mortality. Objective: To determine in a population-based study …

Background: The rapid rise in the availability and use of pharmaceutical agents, and
particularly polypharmacy, directly increases the risk for patients to experience adverse drug …

Background Adverse drug events, the unintended and harmful effects of medications, are
important outcome measures in health services research. Yet no universally accepted set of …

Background For over 20 years, researchers wanting to record, discuss and compare drug-
related problems (DRPs) have had the task of choosing between a multiplicity of …

Aim: Although health authorities have set pharmacogenetic (PGx) markers on labels of
hundreds of drugs, the use of PGx in clinical care remains infrequent. The adoption of PGx …