Matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) imaging mass
spectrometry (IMS) is an evolving technique in cancer diagnostics and combines the …

In pharmaceutical research, understanding the biodistribution, accumulation and
metabolism of drugs in tissue plays a key role during drug discovery and development. In …

Osteoarthritis (OA), characterized by degeneration of the cartilaginous tissue in articular
joints, severely impairs mobility in many people worldwide. The degeneration is thought to …

Recent advancements in Matrix Assisted Laser Desorption/Ionisation (MALDI) Mass
Spectrometry Imaging (MSI) technology have enabled the analysis of formalin-fixed paraffin …

The well-characterized cellular and structural components of the kidney show distinct
regional compositions and distribution of lipids. In order to more fully analyze the renal …

Shiga toxin (Stx)-mediated injury of the kidneys and the brain represent the major
extraintestinal complications in humans upon infection by enterohemorrhagic Escherichia …

Enterohemorrhagic Escherichia coli (EHEC) are the human pathogenic subset of Shiga
toxin (Stx)-producing E. coli (STEC). EHEC are responsible for severe colon infections …

The increasing analytical speed of mass-spectrometry imaging (MSI) has led to growing
interest in the medical field. Acute kidney injury is a severe disease with high morbidity and …

Prevalence of immune-mediated glomerulonephritis has increased in preclinical toxicity
studies, with more frequent use of biotherapeutic agents (especially antigenic humanized …

Intracapillary foam cell infiltration with podocyte alterations is a characteristic pathology of
focal segmental glomerulosclerosis (FSGS). We investigated the possible role of podocyte …