1H magnetic resonance spectroscopic imaging of deuterated glucose and of neurotransmitter metabolism at 7 T in the human brain
Impaired glucose metabolism in the brain has been linked to several neurological disorders.
Positron emission tomography and carbon-13 magnetic resonance spectroscopic imaging …
Positron emission tomography and carbon-13 magnetic resonance spectroscopic imaging …
[HTML][HTML] The principle of 'brain energy on demand'and its predictive power for stress, sleep, stroke, obesity and diabetes
A Peters, M Sprengell, B Kubera - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Does the brain actively draw energy from the body when needed? There are different
schools of thought regarding energy metabolism. In this study, the various theoretical …
schools of thought regarding energy metabolism. In this study, the various theoretical …
Simultaneous BOLD-fMRI and constant infusion FDG-PET data of the resting human brain
Abstract Simultaneous [18 F]-fluorodeoxyglucose positron emission tomography and
functional magnetic resonance imaging (FDG-PET/fMRI) provides the capability to image …
functional magnetic resonance imaging (FDG-PET/fMRI) provides the capability to image …
PET-based brain molecular connectivity in neurodegenerative disease
JU Hanania, E Reimers, CWJ Bevington… - Current Opinion in …, 2024 - journals.lww.com
Connectivity approaches are poised to greatly enhance the information that can be extracted
from molecular imaging. While currently mostly contributing to enhancing understanding of …
from molecular imaging. While currently mostly contributing to enhancing understanding of …
[HTML][HTML] 2H labeling enables non-invasive 3D proton MR imaging of glucose and neurotransmitter metabolism at 7T in the human brain
The map** of impaired brain glucose metabolism is often used to understand brain
diseases. However, current methods for imaging metabolism are limited by low sensitivities …
diseases. However, current methods for imaging metabolism are limited by low sensitivities …
Cortical excitatory and inhibitory correlates of the fronto-limbic circuit in major depression and differential effects of left frontal brain stimulation in a randomized sham …
Background Major depressive disorder (MDD), particularly treatment-resistant ones, is
associated with abnormal fronto-limbic glucose metabolism. 10-Hz repetitive transcranial …
associated with abnormal fronto-limbic glucose metabolism. 10-Hz repetitive transcranial …
Hybrid PET-MRI for early detection of dopaminergic dysfunction and microstructural degradation involved in Parkinson's disease
S Shang, D Li, Y Tian, R Li, H Zhao, L Zheng… - Communications …, 2021 - nature.com
Dopamine depletion and microstructural degradation underlie the neurodegenerative
processes in Parkinson's disease (PD). To explore early alterations and underlying …
processes in Parkinson's disease (PD). To explore early alterations and underlying …
Abnormal default mode network could be a potential prognostic marker in patients with disorders of consciousness
J Zhang, E Zhang, C Yuan, H Zhang, X Wang… - Clinical Neurology and …, 2022 - Elsevier
Objectives The study aimed to investigate disorders of consciousness (DOC) mechanisms of
patients with severe traumatic brain injury (sTBI) related to default mode network (DMN) and …
patients with severe traumatic brain injury (sTBI) related to default mode network (DMN) and …
Combining CRISPR-Cas9 and brain imaging to study the link from genes to molecules to networks
Receptors, transporters, and ion channels are important targets for therapy development in
neurological diseases, but their mechanistic role in pathogenesis is often poorly understood …
neurological diseases, but their mechanistic role in pathogenesis is often poorly understood …
An in vivo multimodal feasibility study in a rat brain tumour model using flexible multinuclear MR and PET systems
CH Choi, C Stegmayr, A Shymanskaya, WA Worthoff… - EJNMMI physics, 2020 - Springer
Background In addition to the structural information afforded by 1 H MRI, the use of X-nuclei,
such as sodium-23 (23 Na) or phosphorus-31 (31 P), offers important complementary …
such as sodium-23 (23 Na) or phosphorus-31 (31 P), offers important complementary …