Development of novel tetrapyrrole structure photosensitizers for cancer photodynamic therapy

N Plekhova, O Shevchenko, O Korshunova… - Bioengineering, 2022 - mdpi.com
The effectiveness of photodynamic therapy (PDT) is based on the triad effects of
photosensitizer (PS), molecular oxygen and visible light on malignant tumors. Such complex …

Photodynamic disinfection and its role in controlling infectious diseases

RT Aroso, FA Schaberle, LG Arnaut… - Photochemical & …, 2021 - Springer
Photodynamic therapy is witnessing a revival of its origins as a response to the rise of multi-
drug resistant infections and the shortage of new classes of antibiotics. Photodynamic …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

DJ Harvey - Mass Spectrometry Reviews, 2023 - Wiley Online Library
This review is the tenth update of the original article published in 1999 on the application of
matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of …

Dissecting the interactions between chlorin e6 and human serum albumin

A Marconi, EJ Mattioli, F Ingargiola, G Giugliano… - Molecules, 2023 - mdpi.com
Chlorin e6 (Ce6) is among the most used sensitizers in photodynamic (PDT) and
sonodynamic (SDT) therapy; its low solubility in water, however, hampers its clinical …

Conjugates of tetrapyrrolic macrocycles as potential anticancer target-oriented photosensitizers

AM Korolchuk, VA Zolottsev, AY Misharin - Topics in Current Chemistry, 2023 - Springer
Photodynamic therapy is a minimally invasive treatment of tumors using photosensitizers,
light, and reactive oxygen species, which can destroy cellular structures. With the …

Putting a “C60 Ball” and Chain to Chlorin e6 Improves Its Cellular Uptake and Photodynamic Performances

M Di Sante, A Kaltenbrunner, M Lombardo, A Danielli… - Pharmaceuticals, 2023 - mdpi.com
Chlorin e6 (Ce6) and fullerene (C60) are among the most used photosensitizers (PSs) for
photodynamic therapy (PDT). Through the combination of the chemical and photophysical …

d-Mannose-appended 5, 15-diazaporphyrin for photodynamic therapy

LMA Ali, K Miyagawa, N Fukui, M Onofre… - Organic & …, 2022 - pubs.rsc.org
5, 15-Diazaporphyrin appended with D-mannose moieties was prepared through Suzuki–
Miyaura cross-coupling reaction and SN2 alkylation. The resultant diazaporphyrin was …

Beneficial effects on T cells by photodynamic therapy with talaporfin enhance cancer immunotherapy

EM Ezzaldeen, T Yaguchi, R Imagawa… - International …, 2025 - academic.oup.com
Photodynamic therapy (PDT), a local cancer treatment using photosensitizers, has been
reported to enhance antitumor immune responses by inducing immunogenic cell death …

Maltotriose–Chlorin e6 Conjugate Linked via Tetraethyleneglycol as an Advanced Photosensitizer for Photodynamic Therapy. Synthesis and Antitumor Activities …

A Narumi, R Rachi, H Yamazaki, S Kawaguchi… - ACS …, 2021 - ACS Publications
Glycoconjugated chlorins represent a promising class of compounds that meet the
requirements for the third-generation photosensitizer (PS) for photodynamic therapy (PDT) …

On the need for standardized reporting of photophysical parameters of in vitro photodynamic therapy studies

M Dick, H Jamal, YR Liu, JP Celli, L Lilge - … and Photodynamic Therapy, 2023 - Elsevier
In vitro dose escalation experiments are one of the first gatekeepers in therapeutic
evaluation and development. This also holds for evaluating novel photosensitizers (PS) and …