CRISPR/Cas9 therapeutics: progress and prospects
T Li, Y Yang, H Qi, W Cui, L Zhang, X Fu, X He… - … and Targeted Therapy, 2023 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …
protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases …
TRP (transient receptor potential) ion channel family: Structures, biological functions and therapeutic interventions for diseases
Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …
SARS‐CoV‐2 variants and vulnerability at the global level
Numerous variants of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
pandemic have evolved. Viral variants may evolve with harmful susceptibility to the immunity …
pandemic have evolved. Viral variants may evolve with harmful susceptibility to the immunity …
Two years into the COVID-19 pandemic: lessons learned
SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …
[PDF][PDF] Revolutionizing infectious disease management in low-resource settings: The impact of rapid diagnostic technologies and portable devices
Olatunji, Olaboye, Maha, Kolawole, & Abdul, P. No. 1417-1432 Page 1418 services to
remote and underserved areas. These devices are designed to be user-friendly, requiring …
remote and underserved areas. These devices are designed to be user-friendly, requiring …
[HTML][HTML] Bone/cartilage organoid on-chip: Construction strategy and application
Y Hu, H Zhang, S Wang, L Cao, F Zhou, Y **g, J Su - Bioactive Materials, 2023 - Elsevier
The necessity of disease models for bone/cartilage related disorders is well-recognized, but
the barrier between ex-vivo cell culture, animal models and the real human body has been …
the barrier between ex-vivo cell culture, animal models and the real human body has been …
Immune evasion of neutralizing antibodies by SARS-CoV-2 Omicron
Since its emergence at the end of 2019, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has caused the infection of more than 600 million people worldwide and has …
(SARS-CoV-2) has caused the infection of more than 600 million people worldwide and has …
Glow-in-the-dark infectious disease diagnostics using Crispr-Cas9-based Split luciferase complementation
HJ van der Veer, EA van Aalen… - ACS Central …, 2023 - ACS Publications
Nucleic acid detection methods based on CRISPR and isothermal amplification techniques
show great potential for point-of-care diagnostic applications. However, most current …
show great potential for point-of-care diagnostic applications. However, most current …
Digital PCR applications in the SARS-CoV-2/COVID-19 era: a roadmap for future outbreaks
The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global public health …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global public health …
Next-generation CRISPR-based diagnostic tools for human diseases
Accurate diagnosis of human diseases is crucial for effective prevention, clinical treatment,
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …