A systematic review of bleomycin-induced gonadotoxicity: mechanistic implications for male reproductive health and fertility

AL de Almeida, A Fortuna, M Sousa, R Sá - Reproductive Toxicology, 2024 - Elsevier
Long-term cancer treatment complications in men include testicular dysfunction and
infertility. Although various chemotherapies have been studied, there is limited evidence on …

[HTML][HTML] Immune checkpoint inhibitors as a threat to reproductive function: A systematic review

Y Zhao, Y Li, X Liu, S Wen, J Cao, J Cui… - Critical Reviews in …, 2023 - Elsevier
In recent years, the indications for immunotherapy in cancer treatment have been
expanding. The increased risk of cancer in young people, coupled with the fact that many …

[HTML][HTML] In Vitro Generation of Haploid Germ Cells from Human XY and XXY Immature Testes in a 3D Organoid System

G Galdon, NP Zarandi, NA Deebel, S Zhang, O Cornett… - Bioengineering, 2024 - mdpi.com
Increasing survival rates of children following cancer treatment have resulted in a significant
population of adult survivors with the common side effect of infertility. Additionally, the …

Maternal supplementation of alpha-lipoic acid ameliorates prenatal cytarabine-induced mutilation in reproductive development and function in F1 male adult rats

KN Chilaka, R Namoju - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
Aims Cytarabine (CYT), a prevalent anticancer drug for blood cancers, detrimentally affects
male reproductive development and function. Alpha-lipoic acid (ALA), a universal …

Analysis of sperm separation protocols for isolating cryopreserved human spermatozoa

AJ Hungerford, HW Bakos… - Reproduction and …, 2023 - raf.bioscientifica.com
Graphical abstract Abstract Sperm cryopreservation is a valuable tool for the long-term
preservation of male fertility. Thus, determining the optimal technique for isolating …

[HTML][HTML] Self-disclosure, perceived social support, and reproductive concerns among young male cancer patients in China: a mediating model analysis

L Wu, X Chen, T Dong, W Yan, L Wang, W Li - Asia-Pacific Journal of …, 2024 - Elsevier
Objective Many young male cancer patients experience reproductive concerns. Self-
disclosure might be able to improve patients' perceived social support and reproductive …

Attenuation of doxorubicin-induced hypothalamic-pituitary-testicular axis dysfunction by diphenyl diselenide involves suppression of hormonal deficits, oxido …

AA Babalola, AR Adelowo, OF Da-Silva, CN Ikeji… - Journal of Trace …, 2023 - Elsevier
Background Doxorubicin (DOX) is one of the popular anti-cancer drugs in the world and
several literatures have implicated it in various toxicities especially cardiotoxicity and …

[HTML][HTML] The consequences of climate change and male reproductive health: A review of the possible impact and mechanisms

RE Akhigbe, PA Oyedokun, TM Akhigbe… - … and Biophysics Reports, 2025 - Elsevier
A global decline in male fertility has been reported, and climate change is considered a
major cause of this. Climate change refers to long-term shifts in temperatures and weather …

Navigating an uncertain future: a qualitative study exploring thoughts about fertility and oncofertility counseling among young men with cancer

L Bentsen, M Aagesen, M Hjerming… - Supportive Care in …, 2025 - Springer
Purpose This study aimed to explore the thoughts and experiences of young men with
cancer regarding the risk of infertility and the oncofertility counseling they received at …

Comparative Efficacy of Different Cognitive Behavior Therapy Delivery Formats for Depression in Patients With Cancer: A Network Meta‐Analysis of Randomized …

L Duan, S Zhang, Q Yan, X Hu - Psycho‐Oncology, 2025 - Wiley Online Library
Background Cognitive behavior therapy (CBT) has been shown to be effective in improving
depression in patients with cancer. However, diversity exists in the CBT delivery formats …