Develo** neurons connect in specific and stereotyped ways to form the complex circuits
that underlie brain function. By comparison to earlier steps in neural development, progress …

Background Migraine is a complex neurovascular disorder with a strong genetic component.
There are rare monogenic forms of migraine, as well as more common polygenic forms; …

Semaphorins, originally discovered as guidance cues for develo** axons, are involved in
many processes that shape the nervous system during development, from neuronal …

In mammals, taste buds typically contain 50–100 tightly packed taste-receptor cells (TRCs),
representing all five basic qualities: sweet, sour, bitter, salty and umami,. Notably, mature …

Rationale: Peripheral nerves are unique in their remarkable elasticity. Schwann cells (SCs),
important components of the peripheral nervous system (PNS), are constantly subjected to …

Spinal motor axons traverse large distances to innervate target muscles, thus requiring local
control of cellular events for proper functioning. To interrogate axon-specific processes we …

Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …

Among the diverse interneuron subtypes in the neocortex, chandelier cells (ChCs) are the
only population that selectively innervate pyramidal neurons (PyNs) at their axon initial …

Highlights•The protein machinery at inhibitory synapses is more complex than
anticipated.•Many new synapse organizers have recently been identified.•Major progress …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel type b
coronavirus responsible for the COVID-19 pandemic. With over 224 million confirmed …