Many heat transfer and fluid flow problems are multiscale in nature, and the multiscale
numerical methods are needed to solve the problems by considering the phenomena in all …

We argue that, despite the fact that the field of multiscale modelling and simulation has
enjoyed significant success within the past decade, it still holds many open questions that …

Many important scientific problems are inherently multi scale. This is, for instance, the case
in models in material science or environmental science. A big challenge is to formulate …

We expect that multiscale simulations will be one of the main high performance computing
workloads in the exascale era. We propose multiscale computing patterns as a generic …

We review a methodology to design, implement and execute multi-scale and multi-science
numerical simulations. We identify important ingredients of multi-scale modelling and give a …

Multiscale modeling is a systematic approach for the development of high-fidelity models of
complex systems. However, multiscale models are often extremely computationally …

Re-establishing a functional endothelium following endovascular treatment is an important
factor in arresting neointimal proliferation. In this study, both histology (in vivo) and …

In this paper, we report on the experimental results of running a large, tightly coupled,
distributed multiscale computation over a hybrid High Performance Computing (HPC) …

Agent-based modeling (ABM) is a flexible and simulation-friendly modeling approach.
Ambient-oriented modeling is effective for systems containing ambient and spatial …

This discussion paper introduces the concept of the Virtual Artery as a multiscale model for
arterial physiology and pathologies at the physics–chemistry–biology (PCB) interface. The …