Understanding and preventing contrast-induced acute kidney injury

M Fähling, E Seeliger, A Patzak… - Nature Reviews …, 2017 - nature.com
Contrast-induced acute kidney injury (CIAKI) occurs in up to 30% of patients who receive
iodinated contrast media and is generally considered to be the third most common cause of …

The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis?

F Genovese, AA Manresa, DJ Leeming… - Fibrogenesis & tissue …, 2014 - Springer
Interstitial fibrosis is the common endpoint of end-stage chronic kidney disease (CKD)
leading to kidney failure. The clinical course of many renal diseases, and thereby of CKD, is …

A basic science view of acute kidney injury biomarkers

JR Charlton, D Portilla, MD Okusa - Nephrology Dialysis …, 2014 - academic.oup.com
Over the last decade, significant progress has been made in the identification and validation
of novel biomarkers as well as refinements in the use of serum creatinine as a marker of …

Nephrotoxicity of iodinated contrast media: From pathophysiology to prevention strategies

AL Faucon, G Bobrie, O Clément - European journal of radiology, 2019 - Elsevier
Iodinated contrast media (ICM) induced acute kidney injury (AKI) accounts for 11% of cases
of AKI and is its third most common cause in hospitalized patients. However, the …

Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice

S Arai, K Kitada, T Yamazaki, R Takai, X Zhang… - Nature medicine, 2016 - nature.com
Acute kidney injury (AKI) is associated with prolonged hospitalization and high mortality, and
it predisposes individuals to chronic kidney disease. To date, no effective AKI treatments …

The predictive role of the biomarker kidney molecule-1 (KIM-1) in acute kidney injury (AKI) cisplatin-induced nephrotoxicity

DM Tanase, EM Gosav, S Radu, CF Costea… - International journal of …, 2019 - mdpi.com
Acute kidney injury (AKI) following platinum-based chemotherapeutics is a frequently
reported serious side-effect. However, there are no approved biomarkers that can properly …

[HTML][HTML] Kidney injury molecule 1 (KIM-1): a multifunctional glycoprotein and biological marker

ТА Karmakova, NS Sergeeva, КY Kanukoev… - Современные …, 2021 - cyberleninka.ru
KIM-1 (kidney injury molecule 1) is a transmembrane glycoprotein also known as HAVcr-1
and TIM-1 belongs to the T-cell immunoglobulin and mucin domain family (TIM) of proteins …

Exercise training improves diabetic renal injury by reducing fetuin-A, oxidative stress and inflammation in type 2 diabetic rats

S Saberi, M Askaripour, M Khaksari, MA Rajizadeh… - Heliyon, 2024 - cell.com
Background Diabetic kidney disease (DKD) stands as a primary contributor to end-stage
renal disease, associated with heightened mortality in cardiovascular diseases. This study …

Urinary kidney injury molecule-1 in renal disease

RN Moresco, GV Bochi, CS Stein, JAM De Carvalho… - Clinica chimica acta, 2018 - Elsevier
Abstract Kidney injury molecule-1 (KIM-1), a type l transmembrane glycoprotein, is
recognized as a potential biomarker for detection of tubular injury in the main renal …

Advances in understanding and treating diabetic kidney disease: focus on tubulointerstitial inflammation mechanisms

C Xu, X Ha, S Yang, X Tian, H Jiang - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetic kidney disease (DKD) is a serious complication of diabetes that can lead to end-
stage kidney disease. Despite its significant impact, most research has concentrated on the …