Thyroid hormone action is predominantly mediated by thyroid hormone receptors (THRs),
which are encoded by the thyroid hormone receptor α (THRA) and thyroid hormone receptor …

The hypothalamus‐pituitary‐thyroid (HPT) axis determines the set point of thyroid hormone
(TH) production. Hypothalamic thyrotropin‐releasing hormone (TRH) stimulates the …

BACKGROUND: Thyroid hormone receptors TRα1, TRβ1 and TRβ2 are broadly expressed
and exert a pleiotropic influence on many developmental and homeostatic processes …

Pesticides acting as endocrine disrupting chemicals disrupt the homeostasis of body
metabolism. The present study elucidated that the low dose coexposure of thyroid disrupting …

Thyroid hormone receptors (TRs) are members of the nuclear receptor superfamily of ligand-
activated transcription factors involved in cell differentiation, growth, and homeostasis …

Resistance to thyroid hormone beta (RTHβ) is a syndrome characterized by reduced
responsiveness of peripheral tissues to thyroid hormone (TH). In most cases, the disorder is …

Brominated phenolic compounds (BPCs) are found in the environment, and in human and
wildlife tissues, and some are considered to have endocrine disrupting activities. The goal of …

Thyroid hormone (TH) is essential throughout life. Its actions are mediated primarily by the
thyroid hormone receptor (THR), which is a nuclear receptor. Classically, the THRs act as …

Even though the presence of endocrine disrupting chemicals (EDCs) with thyroid hormone
(TH)-like activities in the environment is a major health concern, the methods for their …

Numerous manmade chemicals released into the environment can interfere with normal,
hormonally regulated biological processes to adversely affect the development and …