New finds in the palaeoanthropological and genomic records have changed our view of the
origins of modern human ancestry. Here we review our current understanding of how the …

Connectivity is classically considered an emergent property of landscapes encapsulating
individuals' flows across space. However, its operational use requires a precise …

Population size history is essential for studying human evolution. However, ancient
population size history during the Pleistocene is notoriously difficult to unravel. In this study …

High-coverage whole-genome sequence studies have so far focused on a limited number of
geographically restricted populations,,,, or been targeted at specific diseases, such as …

Background The dramatic progress in sequencing technologies offers unprecedented
prospects for deciphering the organization of natural populations in space and time …

Charles Darwin changed the course of scientific thinking by showing how evolution
accounts for the stunning diversity and biological complexity of life on earth. Recently, there …

This research advances and empirically establishes the hypothesis that, in the course of the
prehistoric exodus of Homo sapiens out of Africa, variation in migratory distance to various …

For most of the vast span of human history, economic growth was all but nonexistent. Then,
about two centuries ago, some nations began to emerge from this epoch of economic …

Natural killer (NK) cells have roles in immunity and reproduction that are controlled by
variable receptors that recognize MHC class I molecules. The variable NK cell receptors …

Genome-wide patterns of homozygosity runs and their variation across individuals provide a
valuable and often untapped resource for studying human genetic diversity and evolutionary …