Hyperuricemia may occur when there is an excess of uric acid in the blood. Hyperuricemia
may result from increased production or decreased excretion of uric acid. Elevated uric acid …

The association between increased serum urate and hypertension has been a subject of
intense controversy. Extracellular uric acid drives uric acid deposition in gout, kidney stones …

Hyperuricemia is an essential causal risk factor for gout and is associated with
cardiometabolic diseases. Given the limited contribution of East Asian ancestry to genome …

With the widespread popularity of hyperuricemia, it has become a severe threat to human
public health. Accumulating evidence suggests that dietary fructose has a close relationship …

Fructose is often used as a food ingredient due to its low production costs and sweetening
power. In recent years, it has been noticed that people on a Western diet high in fructose …

Urate homeostasis in humans is a complex and highly heritable process that involves ie,
metabolic urate biosynthesis, renal urate reabsorption, as well as renal and extrarenal urate …

Hyperuricemia is a metabolic disease caused by impaired uric acid (UA) metabolism. Ellagic
acid (EA) is a natural small-molecule polyphenolic compound with known antioxidative and …

Background Insulin resistance, hypertension, hyperuricemia, and hypercholesterolemia are
hypothesized to be important intermediates in the relationship between excess body weight …

Hyperuricemia is a risk factor for gout. It has been well observed that a large proportion of
individuals with hyperuricemia have never had a gout flare (s), while some patients with gout …

The relationship between serum uric acid (SUA) and hypertension has been a subject of
increasing interest since the 1870 discovery by Frederick Akbar Mahomed. Several …