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Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?
B Liu, M Li, Z Zhou, X Guan, Y **ang - Journal of autoimmunity, 2020 - Elsevier
The emergent outbreak of coronavirus disease 2019 (COVID-19) has caused a global
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are …
pandemic. Acute respiratory distress syndrome (ARDS) and multiorgan dysfunction are …
Insights into the immuno-pathogenesis of acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) is a clinical syndrome associated with
oxygenation failure resulting from a direct pulmonary or indirect systemic insult. It is a …
oxygenation failure resulting from a direct pulmonary or indirect systemic insult. It is a …
Platelet–neutrophil crosstalk in atherothrombosis
Atherothrombosis is a frequent cause of cardiovascular mortality. It is mostly triggered by
plaque rupture and exposure of the thrombogenic subendothelial matrix, which initiates …
plaque rupture and exposure of the thrombogenic subendothelial matrix, which initiates …
Effect of aspirin on deaths associated with sepsis in healthy older people (ANTISEPSIS): a randomised, double-blind, placebo-controlled primary prevention trial
Background Sepsis is a serious global health issue and a major cause of death and
disability. The availability of a simple, community-based preventive strategy could …
disability. The availability of a simple, community-based preventive strategy could …
RvD1 ameliorates LPS-induced acute lung injury via the suppression of neutrophil infiltration by reducing CXCL2 expression and release from resident alveolar …
HW Zhang, Q Wang, HX Mei, SX Zheng, AM Ali… - International …, 2019 - Elsevier
Acute lung injury (ALI) and/or acute respiratory distress syndrome (ARDS) are life-
threatening critical syndromes characterized by the infiltration of a large number of …
threatening critical syndromes characterized by the infiltration of a large number of …
Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury
Acute respiratory distress syndrome (ARDS) is associated with significant morbidity and
mortality, and neutrophils are critical to its pathogenesis. Neutrophil activation is closely …
mortality, and neutrophils are critical to its pathogenesis. Neutrophil activation is closely …
The role of G protein-coupled receptor in neutrophil dysfunction during sepsis-induced acute respiratory distress syndrome
Y Wang, C Zhu, P Li, Q Liu, H Li, C Yu, X Deng… - Frontiers in …, 2023 - frontiersin.org
Sepsis is defined as a life-threatening dysfunction due to a dysregulated host response to
infection. It is a common and complex syndrome and is the leading cause of death in …
infection. It is a common and complex syndrome and is the leading cause of death in …
Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse
There is no therapeutic intervention proven to prevent acute respiratory distress syndrome
(ARDS). Novel mechanistic insights into the pathophysiology of ARDS are therefore …
(ARDS). Novel mechanistic insights into the pathophysiology of ARDS are therefore …
Emerging drugs for treating the acute respiratory distress syndrome
TD Shaw, DF McAuley, CM O'Kane - Expert opinion on emerging …, 2019 - Taylor & Francis
Introduction: The acute respiratory distress syndrome (ARDS) is a common and catastrophic
condition, with a high mortality rate and economic burden on society. Despite 50 years of …
condition, with a high mortality rate and economic burden on society. Despite 50 years of …
Pulmonary drug delivery devices and nanosystems as potential treatment strategies for acute respiratory distress syndrome (ARDS)
Despite advances in drug delivery technologies, treating acute respiratory distress
syndrome (ARDS) is challenging due to pathophysiological barriers such as lung injury …
syndrome (ARDS) is challenging due to pathophysiological barriers such as lung injury …