MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

Highlights•AMPK is activated by immune and environmental stimuli in T cells.•AMPK
regulates T cell fuel usage in response to nutrient availability.•AMPK control of metabolism …

The ability to interrogate total RNA content of single cells would enable better map** of
the transcriptional logic behind emerging cell types and states. However, current single-cell …

Autosomal dominant polycystic kidney disease (ADPKD) affects an estimated 1 in 1,000
people and slowly progresses to end-stage renal disease (ESRD) in about half of these …

Recent studies have reported intrinsic metabolic reprogramming in Pkd1 knock-out cells,
implicating dysregulated cellular metabolism in the pathogenesis of polycystic kidney …

Chronic lung disease has become a leading cause of death in recent years. Despite several
attempts to discover and develop new therapeutic approaches, patients often suffer a poor …

Skeletal muscle (SM) pain and fatigue are common in Fabry disease (FD). Here, we
undertook the investigation of the energetic mechanisms related to FD-SM phenotype. A …

MiRNAs are class of noncoding RNA important for gene expression regulation in many
plants, animals and viruses. MiRNA clusters contain a set of two or more miRNA encoding …

Non-Hodgkin lymphoma (NHL) is a diverse class of hematological cancers, many of which
arise from germinal center (GC)-experienced B cells. Thus GCs, the sites of antibody affinity …

BACKGROUND Metabolic reprogramming is a hallmark of cancer. MicroRNAs (miRNAs)
have been found to regulate cancer metabolism by regulating genes involved in metabolic …