New technologies have enabled the investigation of biology and human health at an
unprecedented scale and in multiple dimensions. These dimensions include a myriad of …

Network medicine is an emerging area of research dealing with molecular and genetic
interactions, network biomarkers of disease, and therapeutic target discovery. Large-scale …

Abstract Systems Bioinformatics is a relatively new approach, which lies in the intersection of
systems biology and classical bioinformatics. It focuses on integrating information across …

Analogous to genomic sequence alignment that allows for across-species transfer of
biological knowledge between conserved sequence regions, biological network alignment …

In the-omics era, bioinformatics technologies allowed the development of several
approaches useful to analyze biological systems. To provide a deep insight into a biological …

Every alignment algorithm consists of two orthogonal components: an objective function M
measuring the quality of an alignment, and a search algorithm that explores the space of …

Biological network alignment aims to find regions of topological and functional (dis)
similarities between molecular networks of different species. Then, network alignment can …

High-Throughput technologies are producing an increasing volume of data that needs large
amounts of data storage, effective data models and efficient, possibly parallel analysis …

Network alignment (NA) aims to find a node map** that identifies topologically or
functionally similar network regions between molecular networks of different species …

Paralleling the increasing availability of protein-protein interaction (PPI) network data,
several network alignment methods have been proposed. Network alignments have been …