Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning

G Buzsáki - Hippocampus, 2015 - Wiley Online Library
Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

High‐frequency oscillations: the state of clinical research

B Frauscher, F Bartolomei, K Kobayashi… - …, 2017 - Wiley Online Library
Modern electroencephalographic (EEG) technology contributed to the appreciation that the
EEG signal outside the classical Berger frequency band contains important information. In …

Quantitative approaches to guide epilepsy surgery from intracranial EEG

JM Bernabei, A Li, AY Revell, RJ Smith… - Brain, 2023 - academic.oup.com
Over the past 10 years, the drive to improve outcomes from epilepsy surgery has stimulated
widespread interest in methods to quantitatively guide epilepsy surgery from intracranial …

Advances in the development of biomarkers for epilepsy

A Pitkänen, W Löscher, A Vezzani, AJ Becker… - The Lancet …, 2016 - thelancet.com
Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …

Removing high-frequency oscillations: A prospective multicenter study on seizure outcome

J Jacobs, JY Wu, P Perucca, R Zelmann, M Mader… - Neurology, 2018 - neurology.org
Objective To evaluate the use of interictal high-frequency oscillations (HFOs) in epilepsy
surgery for prediction of postsurgical seizure outcome in a prospective multicenter trial …

High‐frequency oscillations in the normal human brain

B Frauscher, N Von Ellenrieder, R Zelmann… - Annals of …, 2018 - Wiley Online Library
Objective High‐frequency oscillations (HFOs) are a promising biomarker for the
epileptogenic zone. It has not been possible, however, to differentiate physiological from …

Facilitation of epileptic activity during sleep is mediated by high amplitude slow waves

B Frauscher, N von Ellenrieder, T Ferrari-Marinho… - Brain, 2015 - academic.oup.com
Epileptic discharges in focal epilepsy are frequently activated during non-rapid eye
movement sleep. Sleep slow waves are present during this stage and have been shown to …

How to record high‐frequency oscillations in epilepsy: a practical guideline

M Zijlmans, GA Worrell, M Dümpelmann, T Stieglitz… - …, 2017 - Wiley Online Library
Objective Technology for localizing epileptogenic brain regions plays a central role in
surgical planning. Recent improvements in acquisition and electrode technology have …

Localization of the epileptogenic zone using high frequency oscillations

A Thomschewski, AS Hincapié, B Frauscher - Frontiers in neurology, 2019 - frontiersin.org
For patients with drug-resistant focal epilepsy, surgery is the therapy of choice in order to
achieve seizure freedom. Epilepsy surgery foremost requires the identification of the …

Variability in the location of high frequency oscillations during prolonged intracranial EEG recordings

SV Gliske, ZT Irwin, C Chestek, GL Hegeman… - Nature …, 2018 - nature.com
The rate of interictal high frequency oscillations (HFOs) is a promising biomarker of the
seizure onset zone, though little is known about its consistency over hours to days. Here we …