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Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension
High blood pressure is one of the most important risk factors for ischaemic heart disease,
stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood …
stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood …
[HTML][HTML] Vascular cognitive impairment (VCI)
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …
NCD Countdown 2030: worldwide trends in non-communicable disease mortality and progress towards Sustainable Development Goal target 3.4
Summary The third UN High-Level Meeting on Non-Communicable Diseases (NCDs) on
Sept 27, 2018, will review national and global progress towards the prevention and control …
Sept 27, 2018, will review national and global progress towards the prevention and control …
A major mechanism for immunomodulation: Dietary fibres and acid metabolites
Diet and the gut microbiota have a profound influence on physiology and health, however,
mechanisms are still emerging. Here we outline several pathways that gut microbiota …
mechanisms are still emerging. Here we outline several pathways that gut microbiota …
Promoting successful cognitive aging: a ten-year update
A decade has passed since we published a comprehensive review in this journal
addressing the topic of promoting successful cognitive aging, making this a good time to …
addressing the topic of promoting successful cognitive aging, making this a good time to …
[HTML][HTML] Summary of the evidence on modifiable risk factors for cognitive decline and dementia: a population-based perspective
M Baumgart, HM Snyder, MC Carrillo, S Fazio… - Alzheimer's & …, 2015 - Elsevier
An estimated 47 million people worldwide are living with dementia in 2015, and this number
is projected to triple by 2050. In the absence of a disease-modifying treatment or cure …
is projected to triple by 2050. In the absence of a disease-modifying treatment or cure …
[HTML][HTML] Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease
AR Nelson, MD Sweeney, AP Sagare… - Biochimica et Biophysica …, 2016 - Elsevier
Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …
cognitive impairment, and dementia. Here, we review the cellular and molecular …
The pathobiology of vascular dementia
C Iadecola - Neuron, 2013 - cell.com
Vascular cognitive impairment defines alterations in cognition, ranging from subtle deficits to
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …
full-blown dementia, attributable to cerebrovascular causes. Often coexisting with …
Post-stroke cognitive impairment: epidemiology, mechanisms and management
JH Sun, L Tan, JT Yu - Annals of translational medicine, 2014 - pmc.ncbi.nlm.nih.gov
Post-stroke cognitive impairment occurs frequently in the patients with stroke. The
prevalence of post-stroke cognitive impairment ranges from 20% to 80%, which varies for …
prevalence of post-stroke cognitive impairment ranges from 20% to 80%, which varies for …
[HTML][HTML] Cerebral small vessel disease and risk of incident stroke, dementia and depression, and all-cause mortality: a systematic review and meta-analysis
SP Rensma, TT van Sloten, LJ Launer… - Neuroscience & …, 2018 - Elsevier
MRI features of cerebral small vessel disease (CSVD), ie white matter hyperintensities,
lacunes, microbleeds, perivascular spaces, and cerebral atrophy, may be associated with …
lacunes, microbleeds, perivascular spaces, and cerebral atrophy, may be associated with …