Malaria: biology and disease

AF Cowman, J Healer, D Marapana, K Marsh - Cell, 2016 - cell.com
Malaria has been a major global health problem of humans through history and is a leading
cause of death and disease across many tropical and subtropical countries. Over the last …

Variant surface antigens of Plasmodium falciparum and their roles in severe malaria

M Wahlgren, S Goel, RR Akhouri - Nature Reviews Microbiology, 2017 - nature.com
Proliferation and differentiation inside erythrocytes are important steps in the life cycle of
Plasmodium spp. To achieve these, the parasites export polypeptides to the surface of …

[HTML][HTML] Cell-cell communication between malaria-infected red blood cells via exosome-like vesicles

N Regev-Rudzki, DW Wilson, TG Carvalho, X Sisquella… - Cell, 2013 - cell.com
Cell-cell communication is an important mechanism for information exchange promoting cell
survival for the control of features such as population density and differentiation. We …

Malaria parasite translocon structure and mechanism of effector export

CM Ho, JR Beck, M Lai, Y Cui, DE Goldberg, PF Egea… - Nature, 2018 - nature.com
The putative Plasmodium translocon of exported proteins (PTEX) is essential for transport of
malarial effector proteins across a parasite-encasing vacuolar membrane into host …

PlasmoDB: a functional genomic database for malaria parasites

C Aurrecoechea, J Brestelli, BP Brunk… - Nucleic acids …, 2009 - academic.oup.com
Abstract PlasmoDB (http://PlasmoDB. org) is a functional genomic database for Plasmodium
spp. that provides a resource for data analysis and visualization in a gene-by-gene or …

Phytophthora Genome Sequences Uncover Evolutionary Origins and Mechanisms of Pathogenesis

BM Tyler, S Tripathy, X Zhang, P Dehal, RHY Jiang… - Science, 2006 - science.org
Draft genome sequences have been determined for the soybean pathogen Phytophthora
sojae and the sudden oak death pathogen Phytophthora ramorum. Oömycetes such as …

A catalogue of the effector secretome of plant pathogenic oomycetes

S Kamoun - Annu. Rev. Phytopathol., 2006 - annualreviews.org
The oomycetes form a phylogenetically distinct group of eukaryotic microorganisms that
includes some of the most notorious pathogens of plants. Oomycetes accomplish parasitic …

Comparative genomics of the neglected human malaria parasite Plasmodium vivax

JM Carlton, JH Adams, JC Silva, SL Bidwell, H Lorenzi… - Nature, 2008 - nature.com
The human malaria parasite Plasmodium vivax is responsible for 25–40% of the∼ 515
million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe …

A translocation signal for delivery of oomycete effector proteins into host plant cells

SC Whisson, PC Boevink, L Moleleki, AO Avrova… - Nature, 2007 - nature.com
Bacterial, oomycete and fungal plant pathogens establish disease by translocation of
effector proteins into host cells, where they may directly manipulate host innate immunity. In …

A secreted effector protein of Laccaria bicolor is required for symbiosis development

JM Plett, M Kemppainen, SD Kale, A Kohler, V Legué… - Current Biology, 2011 - cell.com
Soil-borne mutualistic fungi, such as the ectomycorrhizal fungi, have helped shape forest
communities worldwide over the last 180 million years through a mutualistic relationship …