As manufacturing processes and development of new synthetic compounds increase to
keep pace with the expanding global demand, environmental health, and the effects of …

Zebrafish (Danio rerio) is emerging as an increasingly successful model for translational
research on human neurological disorders. In this review, we appraise the high degree of …

With the high cost and the long‐term assessment of developmental toxicity testing in
mammals, the vertebrate zebrafish has become a useful alternative model organism for high …

Motivation: Collaborative analysis of massive imaging datasets is essential to enable
scientific discoveries. Results: We developed Cytomine to foster active and distributed …

The develo** brain is extremely sensitive to many chemicals. Exposure to neurotoxicants
during development has been implicated in various neuropsychiatric and neurological …

With the advent of imaging probes and live microscopy, developmental biologists have
markedly extended our understanding of the molecular and cellular details of embryonic …

Genetic disorders account for a wide range of renal diseases emerging during childhood
and adolescence. Due to the utilization of modern biochemical and biomedical techniques …

Introduction: Off-target effects represent one of the major concerns in the development of
new pharmaceuticals, requiring large-scale animal toxicity testing. Faster, cheaper and more …

Automated analysis of multi-dimensional microscopy images has become an integral part of
modern research in life science. Most available algorithms that provide sufficient …

A constriction in the neural tube at the junction of the midbrain and hindbrain is a conserved
feature of vertebrate embryos. The constriction is a defining feature of the midbrain …