Micro-electrode-dot-array digital microfluidic biochips: Technology, design automation, and test techniques

Z Zhong, Z Li, K Chakrabarty, TY Ho… - IEEE Transactions on …, 2018 - ieeexplore.ieee.org
Digital microfluidic biochips (DMFBs) are being increasingly used for DNA sequencing, point-
of-care clinical diagnostics, and immunoassays. DMFBs based on a micro-electrode-dot …

Puddle: A dynamic, error-correcting, full-stack microfluidics platform

M Willsey, AP Stephenson, C Takahashi… - Proceedings of the …, 2019 - dl.acm.org
Microfluidic devices promise to automate wetlab procedures by manipulating small chemical
or biological samples. This technology comes in many varieties, all of which aim to save …

Close-to-optimal placement and routing for continuous-flow microfluidic biochips

A Grimmer, Q Wang, H Yao, TY Ho… - 2017 22nd Asia and …, 2017 - ieeexplore.ieee.org
Continuous-flow microfluidics rapidly evolved in the last decades as a solution to automate
laboratory procedures in molecular biology and biochemistry. Therefore, the physical design …

Exact routing for micro-electrode-dot-array digital microfluidic biochips

O Keszocze, Z Li, A Grimmer, R Wille… - 2017 22nd Asia and …, 2017 - ieeexplore.ieee.org
Digital microfluidics is an emerging technology that provide fluidic-handling capabilities on a
chip. One of the most important issues to be considered when conducting experiments on …

An evolutionary algorithm with indirect representation for droplet routing in digital microfluidic biochips

C Jiang, RQ Yang, B Yuan - Engineering Applications of Artificial …, 2022 - Elsevier
As a revolutionary platform for miniaturizing laboratory procedures, the digital microfluidic
biochip (DMFB) has the advantages of flexibility and re-configurability over its flow-based …

BioScript: Programming safe chemistry on laboratories-on-a-chip

J Ott, T Loveless, C Curtis, M Lesani… - Proceedings of the ACM on …, 2018 - dl.acm.org
This paper introduces BioScript, a domain-specific language (DSL) for programmable
biochemistry which executes on emerging microfluidic platforms. The goal of this research is …

How secure are checkpoint-based defenses in digital microfluidic biochips?

M Shayan, S Bhattacharjee, R Wille… - … on Computer-Aided …, 2020 - ieeexplore.ieee.org
A digital microfluidic biochip (DMFB) is a miniaturized laboratory capable of implementing
biochemical protocols. Fully integrated DMFBs consist of a hardware platform, controller …

A compiler for cyber-physical digital microfluidic biochips

C Curtis, D Grissom, P Brisk - … of the 2018 International Symposium on …, 2018 - dl.acm.org
Programmable microfluidic laboratories-on-a-chip (LoCs) offer the benefits of automation
and miniaturization to the life sciences. This paper presents an updated version of the …

Open-source incubation ecosystem for digital microfluidics—Status and roadmap

X Huang, CC Liang, J Li, TY Ho… - 2019 IEEE/ACM …, 2019 - ieeexplore.ieee.org
Electrowetting-on-dielectric (EWOD) is a mechanism that allows physical handling of liquids
with only electrical signals, such as digitizing a liquid into tiny droplets and manipulating …

Sound valve-control for programmable microfluidic devices

A Grimmer, B Klepic, TY Ho… - 2018 23rd Asia and South …, 2018 - ieeexplore.ieee.org
In the domain of microfluidic devices, a paradigm shift from application-specific to fully-
programmable solutions takes place (a similar development from ASICS to FPGAs has been …