Targeting tumor and bone microenvironment: Novel therapeutic opportunities for castration-resistant prostate cancer patients with bone metastasis

S Li, Y Kang, Y Zeng - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Despite standard hormonal therapy that targets the androgen receptor (AR) attenuates
prostate cancer (PCa) effectively in the initial stage, the tumor ultimately converts to …

The nerve growth factor-delivered signals in prostate cancer and its associated microenvironment: When the dialogue replaces the monologue

M Di Donato, P Giovannelli, A Migliaccio, G Castoria - Cell & Bioscience, 2023 - Springer
Prostate cancer (PC) represents the most diagnosed and the second most lethal cancer in
men worldwide. Its development and progression occur in concert with alterations in the …

Flavonoid-based polymeric nanoparticles: A promising approach for cancer and diabetes treatment

S Maity, A Acharyya, AS Chakraborti - European Polymer Journal, 2022 - Elsevier
Flavonoids are a ubiquitous group of plant metabolites, which exhibit therapeutic potential
like anticarcinogenic and antidiabetic activities through various cellular signaling pathways …

Analysis of genetic biomarkers, polymorphisms in ADME-related genes and their impact on pharmacotherapy for prostate cancer

K Rehman, Z Iqbal, D Zhiqin, H Ayub, N Saba… - Cancer Cell …, 2023 - Springer
Prostate cancer (PCa) is a non-cutaneous malignancy in males with wide variation in
incidence rates across the globe. It is the second most reported cause of cancer death. Its …

[HTML][HTML] Exosomes from prostate cancer cell lines: Isolation optimisation and characterisation

A Bertokova, N Svecova, K Kozics, A Gabelova… - Biomedicine & …, 2022 - Elsevier
Exosomes are considered to be a rich source of biomarkers, hence in this article we
examine the best procedure for their isolation. We examine several isolation procedures …

A novel PSMA-targeted probe for NIRF-guided surgery and photodynamic therapy: Synthesis and preclinical validation

M Capozza, R Stefania, V Dinatale, V Bitonto… - International Journal of …, 2022 - mdpi.com
A total of 20% to 50% of prostate cancer (PCa) patients leave the surgery room with positive
tumour margins. The intraoperative combination of fluorescence guided surgery (FGS) and …

SERS Detection of Breast Cancer‐Derived Exosomes Using a Nanostructured Pt‐Black Template

X Li, M Keshavarz, P Kassanos, Z Kidy… - Advanced Sensor …, 2023 - Wiley Online Library
At present, there are no cancer treatments that are both non‐invasive and highly accurate.
New tests that can diagnose cancer at an early stage would help to facilitate such improved …

Theragnostic applications of mammal and plant-derived extracellular vesicles: latest findings, current technologies, and prospects

NB Ali, AF Abdull Razis, DJ Ooi, KW Chan, N Ismail… - Molecules, 2022 - mdpi.com
The way cells communicate is not fully understood. However, it is well-known that
extracellular vesicles (EVs) are involved. Researchers initially thought that EVs were used …

A small peptide targeting the ligand-induced androgen receptor/filamin a interaction inhibits the invasive phenotype of prostate cancer cells

M Di Donato, P Giovannelli, MV Barone, F Auricchio… - Cells, 2021 - mdpi.com
Prostate cancer (PC) is one of the most widespread malignancies among males worldwide.
The androgen receptor (AR) plays a major role in prostate cancer development and …

Mechanism of tumor-derived extracellular vesicles in prostatic cancer progression through the circFMN2/KLF2/RNF128 axis

S Huang, J Zhao, H Yu, G Chen - Apoptosis, 2023 - Springer
Circular RNAs (circRNAs) are a major type of cargos encapsulated in extracellular vesicles
(EVs) and regulate the progression of prostatic cancer (PC). This study was conducted to …