Amyloids are a broad class of proteins and peptides that can misfold and assemble into long
unbranched fibrils with a cross-β conformation. These misfolding and aggregation events …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a long latency in
the" prodromal" stage, for which there are currently no effective treatments. It is generally …

Aberrant protein aggregation leads to various human diseases, but little is known about the
physical chemical properties of these aggregated proteins in cells. Herein, we developed a …

Unlike amyloid aggregates, amorphous protein aggregates with no defined structures have
been challenging to target and detect in a complex cellular milieu. In this study, we rationally …

The DNA photoswitch [Ru (bpy) 2dppz] 2+(bpy= 2, 2′-bipyridine, dppz= dipyrido [3, 2-a:
2′, 3′-c] phenazine) has attracted much attention and become a powerful tool for studying …

Alzheimer's disease is the most common form of age-related neurodegenerative dementia.
The disease is characterised by the presence of plaques in the cerebral cortex. The major …

Alzheimer's disease (AD) is the most common form of dementia, and is a multi-faceted
disease that is characterized by oxidative stress, metal-ion dysregulation, and the formation …

Alzheimer's disease (AD) is pathologically characterized by the accumulation of β-amyloid
(Aβ) deposits in the parenchymal and cortical brain. In this work, we designed, synthesized …

A major challenge in the Alzheimer's disease (AD) is its timely diagnosis. Amyloid β (Aβ)
aggregates have been proposed as the most viable biomarker for the diagnosis of AD. Here …

Self-assembly of metallointercalators into DNA nanocages is a rapid and facile approach to
synthesize discrete bioinorganic host/guest structures with a high load of metal complexes …