[HTML][HTML] Predicting RNA secondary structures from sequence and probing data
RNA secondary structures have proven essential for understanding the regulatory functions
performed by RNA such as microRNAs, bacterial small RNAs, or riboswitches. This success …
performed by RNA such as microRNAs, bacterial small RNAs, or riboswitches. This success …
A Hitchhiker's guide to RNA–RNA structure and interaction prediction tools
RNA biology has risen to prominence after a remarkable discovery of diverse functions of
noncoding RNA (ncRNA). Most untranslated transcripts often exert their regulatory functions …
noncoding RNA (ncRNA). Most untranslated transcripts often exert their regulatory functions …
Informative RNA base embedding for RNA structural alignment and clustering by deep representation learning
M Akiyama, Y Sakakibara - NAR genomics and bioinformatics, 2022 - academic.oup.com
Effective embedding is actively conducted by applying deep learning to biomolecular
information. Obtaining better embeddings enhances the quality of downstream analyses …
information. Obtaining better embeddings enhances the quality of downstream analyses …
Sequence similarity governs generalizability of de novo deep learning models for RNA secondary structure prediction
X Qiu - PLOS Computational Biology, 2023 - journals.plos.org
Making no use of physical laws or co-evolutionary information, de novo deep learning (DL)
models for RNA secondary structure prediction have achieved far superior performances …
models for RNA secondary structure prediction have achieved far superior performances …
The identification and functional annotation of RNA structures conserved in vertebrates
Structured elements of RNA molecules are essential in, eg, RNA stabilization, localization,
and protein interaction, and their conservation across species suggests a common …
and protein interaction, and their conservation across species suggests a common …
The landscape of the non-canonical RNA-binding site of Gemin5 unveils a feedback loop counteracting the negative effect on translation
R Francisco-Velilla… - Nucleic Acids …, 2018 - academic.oup.com
Gemin5 is a predominantly cytoplasmic protein that downregulates translation, beyond
controlling snRNPs assembly. The C-terminal region harbors a non-canonical RNA-binding …
controlling snRNPs assembly. The C-terminal region harbors a non-canonical RNA-binding …
Long intergenic non-coding RNAs of human chromosome 18: focus on cancers
PV Ershov, EO Yablokov, YV Mezentsev, AS Ivanov - Biomedicines, 2024 - mdpi.com
Malignant neoplasms are characterized by high molecular heterogeneity due to multilevel
deregulation of gene expression and cellular functions. It is known that non-coding RNAs …
deregulation of gene expression and cellular functions. It is known that non-coding RNAs …
RNA threading with secondary structure and sequence profile
Motivation RNA threading aims to identify remote homologies for template-based modeling
of RNA 3D structure. Existing RNA alignment methods primarily rely on secondary structure …
of RNA 3D structure. Existing RNA alignment methods primarily rely on secondary structure …
[PDF][PDF] Clusters of mammalian conserved RNA structures in UTRs associate with RBP binding sites
RNA secondary structures play essential roles in the formation of the tertiary structure and
function of a transcript. Recent genome-wide studies highlight significant potential for RNA …
function of a transcript. Recent genome-wide studies highlight significant potential for RNA …
KnotAli: informed energy minimization through the use of evolutionary information
M Gray, S Chester, H Jabbari - BMC bioinformatics, 2022 - Springer
Background Improving the prediction of structures, especially those containing pseudoknots
(structures with crossing base pairs) is an ongoing challenge. Homology-based methods …
(structures with crossing base pairs) is an ongoing challenge. Homology-based methods …