Non-natural folded polymers (foldamers) display considerable versatility, and the design of
such molecules is of great current interest. In this respect, peptidic foldamers are perhaps …

Peptides and proteins are naturally chiral molecular systems so that sensing their structure
and conformation with chirality-based spectral methods is an obvious and long-used …

Over the past decade, foldamers have progressively emerged as useful architectures to
mimic secondary structures of proteins. Peptidic foldamers, consisting of various amino acid …

Peptide-based drug research has received high attention in the field of medicinal chemistry
over the past decade. For drug design, to improve proteolytic stability, it is desirable to …

Introduction: Foldamers are artificial self-organizing systems with various critical properties:
i) a stable and designable secondary structure; ii) a larger molecular surface as compared …

The engineering of biological molecules is the fundamental concept behind the design of
complex materials with desirable functions. Over the last few decades, peptides and proteins …

Computer-assisted study and design of non-natural peptidomimetics is increasingly
important in the development of novel constructs with widespread applicability. Among these …

Folded polymers are utilized in virtually all vital processes in nature. Non-natural folded
polymers (foldamers) have the potential for being similarly or even more versatile, and the …

Fighting against windmills: Highly homogeneous, well‐defined, and finite “windmill”‐and
square‐rod‐shaped supramolecular architectures were formed by the self‐assembly of a …

The concept of chemically evolvable replicators is central to abiogenesis. Chemical
evolvability requires three essential components: energy-harvesting mechanisms for …