[HTML][HTML] Unraveling the epigenetic tapestry: decoding the impact of epigenetic modifications in hidradenitis suppurativa pathogenesis

EM Nardacchione, PM Tricarico, R Moura, AP d'Adamo… - Genes, 2023 - mdpi.com
Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin disorder, which typically
occurs during puberty or early adulthood. The pathogenesis of HS is complex and …

Rethinking Hidradenitis Suppurativa Management: Insights into Bacterial Interactions and Treatment Evolution

FD Huynh, G Damiani, CG Bunick - Antibiotics, 2024 - mdpi.com
Hidradenitis suppurativa (HS), or acne inversa, is a chronic inflammatory dermatological
condition characterized by painful and recurrent nodules and purulent abscesses. HS can …

Deregulated long non-coding RNAs (lncRNA) as promising biomarkers in hidradenitis suppurativa

U Radhakrishna, U Ratnamala, DD Jhala… - Journal of clinical …, 2024 - mdpi.com
Background/Objectives: In recent times, epigenetics alterations in Hidradenitis suppurativa
(HS) have been explored and exploited translationally to guide investigation of new …

DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa

U Radhakrishna, U Ratnamala, DD Jhala… - Frontiers in …, 2024 - frontiersin.org
Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition that
affects hair follicles in areas with apocrine sweat glands, such as the underarms, groin, and …

Identification of novel genetic risk variants associated with hidradenitis suppurativa in an exome sequencing cohort of 92,455 individuals

RP Metpally, S Vishweswaraiah, S Krishnamurthy… - Dermatology, 2024 - karger.com
Introduction: Hidradenitis suppurativa (HS) is a prevalent and persistent inflammatory skin
disorder, lacking a known cure or effective biomarkers for early diagnosis at present. The …

[HTML][HTML] Impaired Molecular Mechanisms Contributing to Chronic Pain in Patients with Hidradenitis Suppurativa: Exploring Potential Biomarkers and Therapeutic …

U Radhakrishna, MR Kuracha… - International …, 2025 - pmc.ncbi.nlm.nih.gov
Hidradenitis suppurativa (HS) is a chronic skin condition that primarily affects areas with
dense hair follicles and apocrine sweat glands, such as the underarms, groin, buttocks, and …

Single-Cell Transcriptomic and Targeted Genomic Profiling Adjusted for Inflammation and Therapy Bias Reveal CRTAM and PLCB1 as Novel Hub Genes for Anti …

M Gorenjak, B Gole, L Goričan, G Jezernik… - Pharmaceutics, 2024 - mdpi.com
Background: The lack of reliable biomarkers in response to anti-TNFα biologicals hinders
personalized therapy for Crohn's disease (CD) patients. The motivation behind our study is …

[PDF][PDF] Identification and Validation of Telomere-Related Gene Signature in Intervertebral Disc Degeneration

S **e, H **ao, F Zhang, YP Lan, M Luo, S **e Sr… - Cureus, 2024 - cureus.com
This study investigates the role of telomere-related differentially expressed genes (TRDEGs)
in intervertebral disc degeneration (IVDD) through comprehensive bioinformatics analyses …

[PDF][PDF] Hospitalized hidradenitis suppurativa patients at a university clinic: a fifteen-year retrospective analysis of hospitalized patients with a focus on sex differences

D Živanović, M Demenj, M Nikolić… - … Alpina, Pannonica, et …, 2024 - researchgate.net
Introduction: Hidradenitis suppurativa (HS) is a chronic skin disease marked by recurrent
abscesses, sinus tracts, and scarring, often accompanied by systemic symptoms. Diagnosed …