Adipose tissue dysfunction as determinant of obesity-associated metabolic complications

M Longo, F Zatterale, J Naderi, L Parrillo… - International journal of …, 2019 - mdpi.com
Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …

Concise review: mesenchymal stem cells: from roots to boost

A Andrzejewska, B Lukomska, M Janowski - Stem cells, 2019 - academic.oup.com
It was shown as long as half a century ago that bone marrow is a source of not only
hematopoietic stem cells, but also stem cells of mesenchymal tissues. Then the term …

Developmental origins of metabolic diseases

DJ Hoffman, TL Powell, ES Barrett… - Physiological …, 2021 - journals.physiology.org
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications

Z Ghesmati, M Rashid, S Fayezi, F Gieseler… - Reviews in Endocrine …, 2024 - Springer
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …

m6A-binding proteins: the emerging crucial performers in epigenetics

Y Zhao, Y Shi, H Shen, W **e - Journal of hematology & oncology, 2020 - Springer
Abstract N 6-methyladenosine (m 6 A) is a well-known post-transcriptional modification that
is the most common type of methylation in eukaryotic mRNAs. The regulation of m 6 A is …

Adipogenesis as a potential anti-obesity target: A review of pharmacological treatment and natural products

J Jakab, B Miškić, Š Mikšić, B Juranić… - … syndrome and obesity, 2021 - Taylor & Francis
Obesity is recognized as a severe threat to overall human health and is associated with type
2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal …

m6A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7

X Wang, R Wu, Y Liu, Y Zhao, Z Bi, Y Yao, Q Liu… - Autophagy, 2020 - Taylor & Francis
ABSTRACT N 6-methyladenosine (m6A), the most abundant internal modification on
mRNAs in eukaryotes, play roles in adipogenesis. However, the underlying mechanism …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Immunomodulatory and regenerative effects of mesenchymal stem cells and extracellular vesicles: therapeutic outlook for inflammatory and degenerative diseases

S Dabrowska, A Andrzejewska, M Janowski… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent stem cells derived from
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …

Evidence of flavonoids on disease prevention

M Li, M Qian, Q Jiang, B Tan, Y Yin, X Han - Antioxidants, 2023 - mdpi.com
A growing body of evidence highlights the properties of flavonoids in natural foods for
disease prevention. Due to their antioxidative, anti-inflammatory, and anti-carcinogenic …