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Adipose tissue dysfunction as determinant of obesity-associated metabolic complications
Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …
Concise review: mesenchymal stem cells: from roots to boost
It was shown as long as half a century ago that bone marrow is a source of not only
hematopoietic stem cells, but also stem cells of mesenchymal tissues. Then the term …
hematopoietic stem cells, but also stem cells of mesenchymal tissues. Then the term …
Developmental origins of metabolic diseases
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …
as obese, while nearly one-third of children globally experience poor growth and …
An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …
m6A-binding proteins: the emerging crucial performers in epigenetics
Y Zhao, Y Shi, H Shen, W **e - Journal of hematology & oncology, 2020 - Springer
Abstract N 6-methyladenosine (m 6 A) is a well-known post-transcriptional modification that
is the most common type of methylation in eukaryotic mRNAs. The regulation of m 6 A is …
is the most common type of methylation in eukaryotic mRNAs. The regulation of m 6 A is …
Adipogenesis as a potential anti-obesity target: A review of pharmacological treatment and natural products
Obesity is recognized as a severe threat to overall human health and is associated with type
2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal …
2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal …
m6A mRNA methylation controls autophagy and adipogenesis by targeting Atg5 and Atg7
X Wang, R Wu, Y Liu, Y Zhao, Z Bi, Y Yao, Q Liu… - Autophagy, 2020 - Taylor & Francis
ABSTRACT N 6-methyladenosine (m6A), the most abundant internal modification on
mRNAs in eukaryotes, play roles in adipogenesis. However, the underlying mechanism …
mRNAs in eukaryotes, play roles in adipogenesis. However, the underlying mechanism …
[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …
disorders and metabolic syndrome have largely been attributed to genetic background and …
Immunomodulatory and regenerative effects of mesenchymal stem cells and extracellular vesicles: therapeutic outlook for inflammatory and degenerative diseases
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent stem cells derived from
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …
Evidence of flavonoids on disease prevention
A growing body of evidence highlights the properties of flavonoids in natural foods for
disease prevention. Due to their antioxidative, anti-inflammatory, and anti-carcinogenic …
disease prevention. Due to their antioxidative, anti-inflammatory, and anti-carcinogenic …