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Insights into the assembly and regulation of the bacterial divisome
The ability to split one cell into two is fundamental to all life, and many bacteria can
accomplish this feat several times per hour with high accuracy. Most bacteria call on an …
accomplish this feat several times per hour with high accuracy. Most bacteria call on an …
Stay on track—revelations of bacterial cell wall synthesis enzymes and things that go by single-molecule imaging
In this review, we explore the regulation of septal peptidoglycan (sPG) synthesis in bacterial
cell division, a critical process for cell viability and proper morphology. Recent single …
cell division, a critical process for cell viability and proper morphology. Recent single …
Cell wall synthesis and remodelling dynamics determine division site architecture and cell shape in Escherichia coli
The bacterial division apparatus catalyses the synthesis and remodelling of septal
peptidoglycan (sPG) to build the cell wall layer that fortifies the daughter cell poles …
peptidoglycan (sPG) to build the cell wall layer that fortifies the daughter cell poles …
Peptidoglycan synthesis drives a single population of septal cell wall synthases during division in Bacillus subtilis
Bacterial cell division requires septal peptidoglycan (sPG) synthesis by the divisome
complex. Treadmilling of the essential tubulin homologue FtsZ has been implicated in septal …
complex. Treadmilling of the essential tubulin homologue FtsZ has been implicated in septal …
Conformational changes in the essential E. coli septal cell wall synthesis complex suggest an activation mechanism
The bacterial divisome is a macromolecular machine composed of more than 30 proteins
that controls cell wall constriction during division. Here, we present a model of the structure …
that controls cell wall constriction during division. Here, we present a model of the structure …
An updated model of the divisome: regulation of the septal peptidoglycan synthesis machinery by the divisome
The synthesis of a peptidoglycan septum is a fundamental part of bacterial fission and is
driven by a multiprotein dynamic complex called the divisome. FtsW and FtsI are essential …
driven by a multiprotein dynamic complex called the divisome. FtsW and FtsI are essential …
Assembly dynamics of FtsZ and DamX during infection-related filamentation and division in uropathogenic E. coli
During infection of bladder epithelial cells, uropathogenic Escherichia coli (UPEC) can stop
dividing and grow into highly filamentous forms. Here, we find that some filaments of E. coli …
dividing and grow into highly filamentous forms. Here, we find that some filaments of E. coli …
Integration of cell wall synthesis and chromosome segregation during cell division in Caulobacter
To divide, bacteria must synthesize their peptidoglycan (PG) cell wall, a protective meshwork
that maintains cell shape. FtsZ, a tubulin homolog, dynamically assembles into a midcell …
that maintains cell shape. FtsZ, a tubulin homolog, dynamically assembles into a midcell …
[HTML][HTML] The divisome is a self-enhancing machine in Escherichia coli and Caulobacter crescentus
H Gong, D Yan, Y Cui, Y Li, J Yang, W Yang… - Nature …, 2024 - nature.com
During bacterial cytokinesis, polymers of the bacterial tubulin FtsZ coalesce into the Z ring to
orchestrate divisome assembly and septal cell wall synthesis. Previous studies have found …
orchestrate divisome assembly and septal cell wall synthesis. Previous studies have found …
[HTML][HTML] A dynamic duo: Understanding the roles of FtsZ and FtsA for Escherichia coli cell division through in vitro approaches
Bacteria divide by binary fission. The protein machine responsible for this process is the
divisome, a transient assembly of more than 30 proteins in and on the surface of the …
divisome, a transient assembly of more than 30 proteins in and on the surface of the …