Cancer, which is the uncontrolled growth of cells, is the second leading cause of death after
heart disease. Targeting drugs, especially to specific genes and proteins involved in growth …

Fluoro-containing heterocycles are widely applied in agricultural, medicinal, imaging,
materials science and other fields due to their unique physical and chemical properties …

Indoles are amongst the most essential class of heteroaromatics in organic chemistry, being
commonly found in biologically active natural products. Indole and its derivatives have …

The transformation of a large‐volume industrial by‐product and stable greenhouse gas
fluoroform (HCF3) to useful products has recently received significant attention. Now, a …

The development of mild, selective, and practical methods for the introduction of fluorine
atom and fluorine-containing functional groups into organic molecules has received …

Structural diversity in heterocyclic chemistry is key to unlocking new properties and modes of
action. In this regard, heterocycles embedding emerging fluorinated substituents hold great …

Incorporation of a trifluoromethyl group with 1, 2, 3-triazoles motifs was described. We
explored a click reaction approach for regioselective synthesis of 1-susbstituted-4 …

We herein present a flexible approach for the incorporation of CF3 units into a predefined
site of electron-rich alkenes that exploits the regiocontrolled introduction of an iodine handle …

A novel and sustainable visible-light-enabled multicomponent reaction involving quinoxalin-
2 (1H)-ones, indoles, and CF 3 SO 2 Na that does not require an external photocatalyst is …

An efficient two-step method for synthesizing 2-(trifluoromethyl)-and 2-(difluoromethyl)
benzoheteroles bearing various substituents was developed. Commercially available HFO …