Properties of gluten intolerance: gluten structure, evolution, pathogenicity and detoxification capabilities

AV Balakireva, AA Zamyatnin Jr - Nutrients, 2016 - mdpi.com
Theterm gluten intolerance may refer to three types of human disorders: autoimmune celiac
disease (CD), allergy to wheat and non-celiac gluten sensitivity (NCGS). Gluten is a mixture …

Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration

R Sankowski, S Mader… - Frontiers in cellular …, 2015 - frontiersin.org
The nervous and immune systems have evolved in parallel from the early bilaterians, in
which innate immunity and a central nervous system (CNS) coexisted for the first time, to …

Autoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feeling

EG Severance, RH Yolken, WW Eaton - Schizophrenia research, 2016 - Elsevier
Autoimmunity, gastrointestinal (GI) disorders and schizophrenia have been associated with
one another for a long time. This paper reviews these connections and provides a context by …

Gluten sensitivity: from gut to brain

M Hadjivassiliou, DS Sanders, RA Grünewald… - The Lancet …, 2010 - thelancet.com
Gluten sensitivity is a systemic autoimmune disease with diverse manifestations. This
disorder is characterised by abnormal immunological responsiveness to ingested gluten in …

Neurologic and psychiatric manifestations of celiac disease and gluten sensitivity

JR Jackson, WW Eaton, NG Cascella, A Fasano… - Psychiatric …, 2012 - Springer
Celiac Disease (CD) is an immune-mediated disease dependent on gluten (a protein
present in wheat, rye or barley) that occurs in about 1% of the population and is generally …

Lactobacilli degrade wheat amylase trypsin inhibitors to reduce intestinal dysfunction induced by immunogenic wheat proteins

A Caminero, JL McCarville, VF Zevallos, M Pigrau… - Gastroenterology, 2019 - Elsevier
Background & Aims Wheat-related disorders, a spectrum of conditions induced by the
ingestion of gluten-containing cereals, have been increasing in prevalence. Patients with …

A potential link between environmental triggers and autoimmunity

A Vojdani - Autoimmune diseases, 2014 - Wiley Online Library
Autoimmune diseases have registered an alarming rise worldwide in recent years.
Accumulated evidence indicates that the immune system′ s ability to distinguish self from …

Losing your nerves? Maybe it's the antibodies

B Diamond, PT Huerta, P Mina-Osorio… - Nature Reviews …, 2009 - nature.com
We propose that the normal immunocompetent B cell repertoire is replete with B cells
making antibodies that recognize brain antigens. Although B cells that are reactive with self …

Celiac disease: from gluten to autoimmunity

C Briani, D Samaroo, A Alaedini - Autoimmunity reviews, 2008 - Elsevier
Celiac disease, also known as gluten-sensitive enteropathy and nontropical sprue, is a
prevalent autoimmune disorder that is triggered by the ingestion of wheat gluten and related …

Markers of celiac disease and gluten sensitivity in children with autism

NM Lau, PHR Green, AK Taylor, D Hellberg… - PloS one, 2013 - journals.plos.org
Objective Gastrointestinal symptoms are a common feature in children with autism, drawing
attention to a potential association with celiac disease or gluten sensitivity. However, studies …