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Sha** faces: genetic and epigenetic control of craniofacial morphogenesis
Major differences in facial morphology distinguish vertebrate species. Variation of facial
traits underlies the uniqueness of human individuals, and abnormal craniofacial …
traits underlies the uniqueness of human individuals, and abnormal craniofacial …
[KNYGA][B] RNA, the epicenter of genetic information
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …
Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes
Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …
PhenoScore quantifies phenotypic variation for rare genetic diseases by combining facial analysis with other clinical features using a machine-learning framework
Several molecular and phenotypic algorithms exist that establish genotype–phenotype
correlations, including facial recognition tools. However, no unified framework that …
correlations, including facial recognition tools. However, no unified framework that …
Microvascular and macrovascular complications of type 2 diabetes mellitus: Exome wide association analyses
Background Type 2 diabetes mellitus (T2DM) is a chronic, metabolic disorder in which
concomitant insulin resistance and β-cell impairment lead to hyperglycemia, influenced by …
concomitant insulin resistance and β-cell impairment lead to hyperglycemia, influenced by …
DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
Transcription factors (TFs) can define distinct cellular identities despite nearly identical DNA-
binding specificities. One mechanism for achieving regulatory specificity is DNA-guided TF …
binding specificities. One mechanism for achieving regulatory specificity is DNA-guided TF …
Increasing diversity in connectomics with the Chinese Human Connectome Project
J Ge, G Yang, M Han, S Zhou, W Men, L Qin… - Nature …, 2023 - nature.com
Cultural differences and biological diversity play important roles in sha** human brain
structure and function. To date, most large-scale multimodal neuroimaging datasets have …
structure and function. To date, most large-scale multimodal neuroimaging datasets have …
Decoding the human face: Progress and challenges in understanding the genetics of craniofacial morphology
Variations in the form of the human face, which plays a role in our individual identities and
societal interactions, have fascinated scientists and artists alike. Here, we review our current …
societal interactions, have fascinated scientists and artists alike. Here, we review our current …
[HTML][HTML] Where the genome meets the connectome: understanding how genes shape human brain connectivity
The integration of modern neuroimaging methods with genetically informative designs and
data can shed light on the molecular mechanisms underlying the structural and functional …
data can shed light on the molecular mechanisms underlying the structural and functional …
Gene-environment interactions in the influence of maternal education on adolescent neurodevelopment using ABCD study
Maternal education was strongly correlated with adolescent brain morphology, cognitive
performances, and mental health. However, the molecular basis for the effects of maternal …
performances, and mental health. However, the molecular basis for the effects of maternal …