FOXO3a is a member of the FOXO subfamily of forkhead transcription factors that mediate a
variety of cellular processes including apoptosis, proliferation, cell cycle progression, DNA …

The phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of
rapamycin (mTOR)-dependent pathway is one of the most integral pathways linked to cell …

Idiopathic pulmonary fibrosis (IPF) is an age-related fatal disease with unknown etiology and
no effective treatment. In this study, we show that primary cultures of fibroblasts derived from …

Airway structure and function are key aspects of normal lung development, growth, and
aging, as well as of lung responses to the environment and the pathophysiology of important …

Oxidative stress is a major cause of morbidity and mortality in human health and disease. In
this review, we focus on the Forkhead Box (Fox) subclass O3 (FoxO3), an extensively …