The CRISPR-Cas system initiated a revolution in genome editing when it was, for the first
time, demonstrated success in the mammalian cells. Today, scientists are able to readily edit …

Messenger RNA (mRNA) has become a promising class of drugs for diverse therapeutic
applications in the past few years. A series of clinical trials are ongoing or will be initiated in …

Two-dimensional nanomaterials are emerging as promising candidates for a wide range of
biomedical applications including tissue engineering, biosensing, pathogen incapacitation …

The emergence of the CRISPR–Cas9 gene editing system has brought much hope and
excitement to the field of gene therapy and the larger scientific community. However, in order …

Genome-editing technology has emerged as a potential tool for treating incurable diseases
for which few therapeutic modalities are available. In particular, discovery of the clustered …

Epithelial cell adhesion molecule (EpCAM) gene encodes a type‐I trans‐membrane
glycoprotein that is overexpressed in many cancerous epithelial cells and promotes tumor …

A vital trial in gene delivery implicates the want for competent and safe delivery systems to
announce therapeutic genes into target cells. Virus vectors are disparaged for genetic …

Mendelian genetics spark the century‐old revolution in genetic engineering. DNA structural
engineering may well spark a similar revolution in chemistry. The first few man‐made DNA …

The development of nonviral gene delivery vehicles for therapeutic applications requires
methods capable of quantifying the association between the genes and their carrier …

To effectively reverse tumor malignization by genome editing, a multi-functional self-
assembled nanovector for the delivery of a genome editing plasmid specifically to tumor …