Intracellular pH regulation by acid-base transporters in mammalian neurons

VA Ruffin, AI Salameh, WF Boron, MD Parker - Frontiers in physiology, 2014 - frontiersin.org
Intracellular pH (pHi) regulation in the brain is important in both physiological and
physiopathological conditions because changes in pHi generally result in altered neuronal …

NBCe1-B/C-knockout mice exhibit an impaired respiratory response and an enhanced renal response to metabolic acidosis

CT Brady, A Marshall, C Zhang, MD Parker - Frontiers in Physiology, 2023 - frontiersin.org
The sodium-bicarbonate cotransporter (NBCe1) has three primary variants: NBCe1-A,-B and-
C. NBCe1-A is expressed in renal proximal tubules in the cortical labyrinth, where it is …

Effects of metabolic acidosis on intracellular pH responses in multiple cell types

AI Salameh, VA Ruffin… - American Journal of …, 2014 - journals.physiology.org
Metabolic acidosis (MAc), a decrease in extracellular pH (pHo) caused by a decrease in
[HCO3−] o at a fixed [CO2] o, is a common clinical condition and causes intracellular pH …

Role of Cl–HCO3 exchanger AE3 in intracellular pH homeostasis in cultured murine hippocampal neurons, and in crosstalk to adjacent astrocytes

AI Salameh, CA Hübner, WF Boron - The Journal of Physiology, 2017 - Wiley Online Library
Key points A polymorphism of human AE3 is associated with idiopathic generalized
epilepsy. Knockout of AE3 in mice lowers the threshold for triggering epileptic seizures. The …

The neurovascular unit

ME O'Donnell - The Blood-Brain Barrier in Health and Disease …, 2015 - api.taylorfrancis.com
The blood brain barrier (BBB) has been viewed classically as a barrier that separates blood
and brain compartments, providing nutrients and other essential molecules to the brain …

[KNIHA][B] Metabolic Acidosis and the Diverse Roles of the Cl/HCO3 Exchanger (AE3) in Intracellular pH Homeostasis

AI Salameh - 2016 - search.proquest.com
In this dissertation, I examine the effects of extracellular metabolic acidosis (MAc)—a
decrease in extracellular pH (pH< sub> o) caused by a decrease in [HCO< sub> 3< sup>–]< …

[CITÁCIA][C] pHresh Blog Intracellular pH regulation by acid-base transporters in mammalian neurons

VA Ruffin, AI Salameh, WF Boron, MD Parker

[CITÁCIA][C] pHresh Articles Intracellular pH regulation by acid-base transporters in mammalian neurons

VA Ruffin, AI Salameh, WF Boron, MD Parker

[CITÁCIA][C] pHresh Articles Intracellular pH regulation by acid-base transporters in mammalian neurons

HA Patel