This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

We take for granted the ability to fall asleep or to snap out of sleep into wakefulness, but
these changes in behavioral state require specific switching mechanisms in the brain that …

Metabolism generates oxygen radicals, which contribute to oncogenic mutations. Activated
oncogenes and loss of tumor suppressors in turn alter metabolism and induce aerobic …

This exceptional book is concerned with the application of fractals and chaos, as well as
other concepts from nonlinear dynamics to biomedical phenomena. Herein we seek to …

Entropy measures are widely applied to quantify the complexity of dynamical systems in
diverse fields. However, the practical application of entropy methods is challenging, due to …

The basic theoretical assumptions of Exercise Physiology and its research directions,
strongly influenced by reductionism, may hamper the full potential of basic science …

In our daily life, we are exposed to uncontrollable and stressful events that disrupt our sleep.
However, the underlying neural mechanisms deteriorating the quality of non-rapid eye …

This book explains the quantitative reasoning required by the fractional calculus applied to
complex physical, social, and biological phenomena. Fractional calculus is inextricably …

Despite the vast progress and achievements in systems biology and integrative physiology
in the last decades, there is still a significant gap in understanding the mechanisms through …

Pathological proteins contributing to Alzheimer's disease (AD) are known to disrupt normal
neuronal functions in the brain, leading to unbalanced neuronal excitatory-inhibitory tone …