Epigenetic mechanisms control various functions throughout the body, from cell fate
determination in development to immune responses and inflammation. Neuroinflammation …

Glioblastoma, also referred to as glioblastoma multiforme (GBM), is grade IV astrocytoma
characterized by being fast-growing and the most aggressive brain tumor. In adults, it is the …

Background Osteosarcoma is one of the five leading causes of cancer death among all
pediatric malignancies. Recent advances in non-coding RNAs suggested that many long …

Brain tumors are responsible for high mortality and morbidity worldwide. The brain tumor
treatment depends on identification of molecular pathways involved in progression and …

Glioblastoma (GBM) is the most common and lethal primary brain malignancy and is
characterized by a high degree of intra and intertumor cellular heterogeneity, a starkly …

Addiction is a leading cause of disease burden worldwide and remains a challenge in
current neuroscience research. Drug-induced lasting changes in gene expression are …

Abstract 1p/19q codeletion, which leads to the abnormal expression of 1p19q genes in
oligodendroglioma, is associated with chemosensitivity and favorable prognosis. Here, we …

Elevated expression of enhancer of zeste homolog 2 (EZH 2), a histone H3K27
methyltransferase, was observed in gliomas harboring telomerase reverse transcriptase …

Recent advancement in understanding cancer etiology has highlighted epigenetic
deregulation as an important phenomenon leading to poor prognosis in glioblastoma …

Persistent infection with high‑risk human papillomavirus is known to cause cervical cancer.
The binding of the costimulatory factors, Tim‑3 and galectin‑9, can cause immune tolerance …