[HTML][HTML] Biomechanical constitutive modeling of the gastrointestinal tissues: a systematic review

B Patel, A Gizzi, J Hashemi, Y Awakeem, H Gregersen… - Materials & …, 2022 - Elsevier
The gastrointestinal (GI) tract is a continuous channel through the body that consists of the
esophagus, the stomach, the small intestine, the large intestine, and the rectum. Its primary …

On a coupled electro-chemomechanical model of gastric smooth muscle contraction

L Klemm, R Seydewitz, M Borsdorf, T Siebert, M Böl - Acta biomaterialia, 2020 - Elsevier
The stomach is a central organ in the gastrointestinal tract that performs a variety of
functions, in which the spatio-temporal organisation of active smooth muscle contraction in …

Computational model of gastric motility with active‐strain electromechanics

S Brandstaeter, A Gizzi, SL Fuchs… - ZAMM‐Journal of …, 2018 - Wiley Online Library
We present an electro‐mechanical constitutive framework for the modeling of gastric motility,
including pacemaker electrophysiology and smooth muscle contractility. In this framework …

Relationships between serum electrolyte concentrations and ileus: a joint clinical and mathematical modeling study

JA Penfold, CI Wells, P Du, A Qian… - Physiological …, 2021 - Wiley Online Library
Aim Prolonged postoperative ileus (PPOI) occurs in around 15% of patients after major
abdominal surgery, posing a significant clinical and economic burden. Significant fluid and …

Effect of inulin on proteome changes induced by pathogenic lipopolysaccharide in human colon

MPL Guarino, A Altomare, S Barera, V Locato… - PLoS …, 2017 - journals.plos.org
In the present study, the protective role of inulin against lipopolysaccharide (LPS)-induced
oxidative stress was evaluated on human colonic mucosa using a proteomic approach …

Smooth muscle strips for intestinal tissue engineering

CM Walthers, M Lee, BM Wu, JCY Dunn - PloS one, 2014 - journals.plos.org
Functionally contracting smooth muscle is an essential part of the engineered intestine that
has not been replicated in vitro. The purpose of this study is to produce contracting smooth …

Supernatants of irritable bowel syndrome mucosal biopsies impair human colonic smooth muscle contractility

MP Guarino, G Barbara, A Cicenia… - …, 2017 - Wiley Online Library
Background Changes in intestinal motility are likely to contribute to irritable bowel syndrome
(IBS) pathophysiology. The aim of the study was to investigate the effects of IBS mucosal …

A new gastro-intestinal mathematical model to study drug bioavailability

M Pompa, M Capocelli, V Piemonte - Medical Engineering & Physics, 2019 - Elsevier
This work focuses on a new mathematical model which describes the gastro-intestinal
absorption of drugs and the effect of food interactions on drugs bioavailability. The model …

Factors correlated with drug use for constipation: perspectives from the 2016 open Japanese National Database

H Mihara, A Murayama, S Nanjo, T Ando, K Tajiri… - BMC …, 2020 - Springer
Background The prevalence of chronic constipation is increased in females and with age or
environmental (low temperature), racial, socioeconomic, and habitual risk factors. The …

Viscoelectromechanics modeling of intestine wall hyperelasticity

A Gizzi, A Pandolfi, M Vasta - International Journal for …, 2016 - Taylor & Francis
Elastic-electroactive biological media are sensitive to both mechanical and electric forces.
Their active behavior is often associated with the presence of reinforcing fibers and their …