Intraepithelial lymphocytes of the intestine

A Lockhart, D Mucida, AM Bilate - Annual review of immunology, 2024 - annualreviews.org
The intestinal epithelium, which segregates the highly stimulatory lumen from the underlying
tissue, harbors one of the largest lymphocyte populations in the body, intestinal …

The influence of AHR on immune and tissue biology

B Stockinger, OE Diaz, E Wincent - EMBO Molecular Medicine, 2024 - embopress.org
The aryl hydrocarbon receptor is a ligand dependent transcription factor which functions as
an environmental sensor. Originally discovered as the sensor for man made pollutants such …

The role of the AHR in host–pathogen interactions

P Barreira-Silva, Y Lian, SHE Kaufmann… - Nature Reviews …, 2024 - nature.com
Host–microorganism encounters take place in many different ways and with different types
of outcomes. Three major types of microorganisms need to be distinguished:(1) pathogens …

Eimeria: Navigating complex intestinal ecosystems

S Weng, E Tian, M Gao, S Zhang, G Yang… - Plos …, 2024 - journals.plos.org
Eimeria is an intracellular obligate apicomplexan parasite that parasitizes the intestinal
epithelial cells of livestock and poultry, exhibiting strong host and tissue tropism. Parasite …

[HTML][HTML] The Janus-facedness of the aryl hydrocarbon receptor pathway Report of the 6th International AHR Meeting: Research, Prevention, Therapy

T Haarmann-Stemmann, D Reichert, X Coumoul… - Biochemical …, 2025 - Elsevier
The ability to sense and process environmental cues is a fundamental aspect of an
organism's biology. The evolutionary ancient transcription factor AHR (aryl hydrocarbon …

The Role of Aryl Hydrocarbon Receptor in Skin Homeostasis: Implications for Therapeutic Strategies in Skin Disorders

J Yang, P Qiao, G Wang, E Dang - Cell Biochemistry and …, 2025 - Wiley Online Library
The aryl hydrocarbon receptor (AhR), a ligand‐activated transcription factor, is extensively
expressed in diverse human organs and plays a pivotal role in mediating the onset …

[HTML][HTML] High Clinical Burden of Cryptosporidium spp. in Adult Patients with Acquired Immunodeficiency in Ghana

FS Sarfo, H Frickmann, A Dompreh, S Osei Asibey… - Microorganisms, 2024 - mdpi.com
There is a paucity of information on the prevalence, risk factors, and clinical correlates of
people living with HIV (PLWH) who are co-infected with Cryptosporidium spp. in the post …

“AHR-ming” host defense against cryptosporidiosis

J Reyes, GS Yap - Cell Host & Microbe, 2023 - cell.com
Globally, cryptosporidiosis is a leading cause of childhood diarrheal disease and is a major
risk factor for malnutrition and impairment of growth and cognitive development. In this issue …

The essential host genome for Cryptosporidium intracellular survival exposes metabolic dependencies that can be leveraged for treatment

NB Marzook, OR Song, L Baumgärtel, N Bernitz… - bioRxiv, 2024 - biorxiv.org
Map** how pathogens interact with their host cells can reveal unexpected pathogen and
host cell biology, paving the way for new treatments. Cryptosporidium is an intracellular …

Mechanisms of CD4+ T Cell-Dependent Resistance Against Cryptosporidium

IS Cohn - 2024 - search.proquest.com
Cryptosporidium species can cause sporadic waterborne diarrhea outbreaks but infections
can be a significant cause of morbidity and mortality in malnourished children and …