Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …

Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

Passage of exogeneous fine particles from the lung into the brain in humans and animals

Y Qi, S Wei, T **n, C Huang, Y Pu… - Proceedings of the …, 2022 - National Acad Sciences
There are still significant knowledge gaps in understanding the intrusion and retention of
exogeneous particles into the central nervous system (CNS). Here, we uncovered various …

Understanding nanomaterial–liver interactions to facilitate the development of safer nanoapplications

J Li, C Chen, T **a - Advanced Materials, 2022 - Wiley Online Library
Nanomaterials (NMs) are widely used in commercial and medical products, such as
cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal …

Converting nanotoxicity data to information using artificial intelligence and simulation

X Yan, T Yue, DA Winkler, Y Yin, H Zhu… - Chemical …, 2023 - ACS Publications
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …

[HTML][HTML] Challenges and opportunities to penetrate the blood-brain barrier for brain cancer therapy

DH Upton, C Ung, SM George, M Tsoli, M Kavallaris… - Theranostics, 2022 - ncbi.nlm.nih.gov
Despite significant advances in research, the prognosis for both primary and secondary
brain cancers remains poor. The blood-brain barrier (BBB) is a complex and unique semi …

Outdoor air pollution and brain development in childhood and adolescence

MM Herting, KL Bottenhorn, DL Cotter - Trends in Neurosciences, 2024 - cell.com
Exposure to outdoor air pollution has been linked to adverse health effects, including
potential widespread impacts on the CNS. Ongoing brain development may render children …

Penetration and translocation of functional inorganic nanomaterials into biological barriers

Y Cong, D Baimanov, Y Zhou, C Chen… - Advanced Drug Delivery …, 2022 - Elsevier
With excellent physicochemical properties, inorganic nanomaterials (INMs) have exhibited a
series of attractive applications in biomedical fields. Biological barriers prevent successful …

Nickel oxide nanoparticles improve soybean yield and enhance nitrogen assimilation

P Zhou, Y Jiang, M Adeel, N Shakoor… - Environmental …, 2023 - ACS Publications
Nickel (Ni) is a trace element beneficial for plant growth and development and could
improve crop yield by stimulating urea decomposition and nitrogen-fixing enzyme activity. A …

[HTML][HTML] Toxicity of zinc oxide nanoparticles: Cellular and behavioural effects

N Fernández-Bertólez, A Alba-González, A Touzani… - Chemosphere, 2024 - Elsevier
Due to their extensive use, the release of zinc oxide nanoparticles (ZnO NP) into the
environment is increasing and may lead to unintended risk to both human health and …