Phytochemicals in Cancer Chemoprevention: Preclinical and Clinical Studies

N Lekhak, HK Bhattarai - Cancer Control, 2024 - journals.sagepub.com
Phytochemicals, chemicals from plants, have garnered huge attention for their potential
ability to prevent cancer. In vivo and preclinical models show that they do so often by …

Unleashing the potential of Genistein and its derivatives as effective therapeutic agents for breast cancer treatment

E Qaed, W Liu, M Almoiliqy, R Mohamed… - … Archives of Pharmacology, 2024 - Springer
Breast cancer remains one of the leading causes of cancer-related deaths among women
worldwide. Genistein (Gen), a phytoestrogen soy isoflavone, has emerged as a promising …

Genistein inhibited endocytosis and fibrogenesis in keloid via CTGF signaling pathways

CT Lu, JL Ko, CC Ou, CT Hsu, YP Hsiao, SC Tang - Genes & Nutrition, 2024 - Springer
Background This study aimed to evaluate soy isoflavones' effect and potential use—
specifically genistein—in treating human keloid fibroblast cells (KFs) and in a keloid tissue …

Genistein inhibited endocytosis and fibrogenesis in transforming growth factor-β1-stimulated keloid via CTGF signaling pathways

CT Lu, JL Ko, CC Ou, CT Hsu, YP Hsiao, SC Tang - 2024 - researchsquare.com
Background: This study aimed to evaluate soy isoflavones' effect and potential use—
specifically genistein—in treating human keloid fibroblast cell lines (KFs) and in a keloid …