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Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with …
O Potterat, M Hamburger - Natural product reports, 2013 - pubs.rsc.org
Covering: up to 2012Since the advent of high-throughput screening (HTS) in the early
1990s, a wealth of innovative technologies have been proposed and implemented for the …
1990s, a wealth of innovative technologies have been proposed and implemented for the …
Epilepsy in the Renaissance: a survey of remedies from 16th and 17th century German herbals
M Adams, SV Schneider, M Kluge, M Kessler… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Before modern anticonvulsive drugs were
developed people in central Europe used herbal remedies to treat epilepsy. Hundreds of …
developed people in central Europe used herbal remedies to treat epilepsy. Hundreds of …
Chemical profiling and quantitation of bioactive compounds in Platycladi Cacumen by UPLC-Q-TOF-MS/MS and UPLC-DAD
B Zhuang, ZM Bi, ZY Wang, L Duan, EH Liu - Journal of Pharmaceutical …, 2018 - Elsevier
Platycladi Cacumen (PC) is a traditional Chinese medicine used for the treatment of
hemorrhages, cough, asthma and hair loss. To get a better understanding of the chemical …
hemorrhages, cough, asthma and hair loss. To get a better understanding of the chemical …
Structure-dependent activity of natural GABA (A) receptor modulators
SS Çiçek - Molecules, 2018 - mdpi.com
GABA (A) receptors are ligand-gated ion channels consisting of five subunits from eight
subfamilies, each assembled in four hydrophobic transmembrane domains. This pentameric …
subfamilies, each assembled in four hydrophobic transmembrane domains. This pentameric …
Combined use of extract libraries and HPLC-based activity profiling for lead discovery: potential, challenges, and practical considerations
O Potterat, M Hamburger - Planta medica, 2014 - thieme-connect.com
A 96-well format plant extract library and a tailored technology platform have been set up for
the discovery of new natural product lead compounds. The considerable advantages of the …
the discovery of new natural product lead compounds. The considerable advantages of the …
Methyl 2-naphthoates with anti-inflammatory activity from Morinda officinalis
C Wang, QH Wei, ZQ **n, LL Tian, JS Zhang, H Zhang - Fitoterapia, 2023 - Elsevier
Chemical fractionation of the EtOH extract of the roots of a traditional Chinese herb, Morinda
officinalis, afforded an array of methyl 2-naphthoate derivatives (1–9) including four pairs of …
officinalis, afforded an array of methyl 2-naphthoate derivatives (1–9) including four pairs of …
Bioactive Diterpenoids from the Stems of Euphorbia royleana
P Wang, C **e, L An, X Yang, Y **, S Yuan… - Journal of Natural …, 2019 - ACS Publications
Two ingenane-(1 and 2), two ent-atisane-(3 and 4), two ent-kaurane-(5 and 6), two ent-
abietane-(7 and 8), and one ent-isopimarane-type (9) diterpenoid and 12 known analogues …
abietane-(7 and 8), and one ent-isopimarane-type (9) diterpenoid and 12 known analogues …
Liver injury protection of Artemisia stechmanniana besser through PI3K/AKT pathway
CB Tian, ML Qin, YL Qian, SS Qin, ZQ Shi… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Artemisia stechmanniana Besser, one of the most
prevalent botanical medicines in Chinese, has been traditionally used for hepatitis …
prevalent botanical medicines in Chinese, has been traditionally used for hepatitis …
[HTML][HTML] GABAA receptor modulation by piperine and a non-TRPV1 activating derivative
S Khom, B Strommer, A Schöffmann… - Biochemical …, 2013 - Elsevier
The action of piperine (the pungent component of pepper) and its derivative SCT-66 ((2E,
4E)-5-(1, 3-benzodioxol-5-yl))-N, N-diisobutyl-2, 4-pentadienamide) on different gamma …
4E)-5-(1, 3-benzodioxol-5-yl))-N, N-diisobutyl-2, 4-pentadienamide) on different gamma …
Phytochemical profiling of Curcuma kwangsiensis rhizome extract, and identification of labdane diterpenoids as positive GABAA receptor modulators
A Schramm, SN Ebrahimi, M Raith, J Zaugg, DC Rueda… - Phytochemistry, 2013 - Elsevier
An ethyl acetate extract of Curcuma kwangsiensis SG Lee & CF Liang (Zingiberaceae)
rhizomes (100 μg/ml) enhanced the GABA-induced chloride current (I GABA) through GABA …
rhizomes (100 μg/ml) enhanced the GABA-induced chloride current (I GABA) through GABA …